相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Personalized RNA Medicine for Pancreatic Cancer
Maud-Emmanuelle Gilles et al.
CLINICAL CANCER RESEARCH (2018)
FDA-Approved Oligonucleotide Therapies in 2017
Cy A. Stein et al.
MOLECULAR THERAPY (2017)
The chemical evolution of oligonucleotide therapies of clinical utility
Anastasia Khvorova et al.
NATURE BIOTECHNOLOGY (2017)
Cellular uptake and trafficking of antisense oligonucleotides
Stanley T. Crooke et al.
NATURE BIOTECHNOLOGY (2017)
Overcoming cellular barriers for RNA therapeutics
Steven F. Dowdy
NATURE BIOTECHNOLOGY (2017)
Asialoglycoprotein receptor 1 mediates productive uptake of N-acetylgalactosamine-conjugated and unconjugated phosphorothioate antisense oligonucleotides into liver hepatocytes
Michael Tanowitz et al.
NUCLEIC ACIDS RESEARCH (2017)
Applying label-free dynamic mass redistribution assay for studying endogenous FPR1 receptor signalling in human neutrophils
Hanna B. Christensen et al.
JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS (2017)
Antisense oligonucleotide and thyroid hormone conjugates for obesity treatment
Yang Cao et al.
SCIENTIFIC REPORTS (2017)
Selective Inhibition of FOXO1 Activator/Repressor Balance Modulates Hepatic Glucose Handling
Fanny Langlet et al.
CELL (2017)
Ligand-Targeted Drug Delivery
Madduri Srinivasarao et al.
CHEMICAL REVIEWS (2017)
New Modalities for Challenging Targets in Drug Discovery
Eric Valeur et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2017)
Efficacy and safety of glucagon-like peptide-1 receptor agonists in type 2 diabetes: A systematic review and mixed-treatment comparison analysis
Zin Z. Htike et al.
DIABETES OBESITY & METABOLISM (2017)
Single-Cell Transcriptome Profiling of Human Pancreatic Islets in Health and Type 2 Diabetes
Asa Segerstolpe et al.
CELL METABOLISM (2016)
FoxO1 Deacetylation Decreases Fatty Acid Oxidation in β-Cells and Sustains Insulin Secretion in Diabetes
Ja Young Kim-Muller et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
Comprehensive Structure-Activity Relationship of Triantennary N-Acetylgalactosamine Conjugated Antisense Oligonucleotides for Targeted Delivery to Hepatocytes
Thazha P. Prakash et al.
JOURNAL OF MEDICINAL CHEMISTRY (2016)
The Medicinal Chemistry of Therapeutic Oligonucleotides
W. Brad Wan et al.
JOURNAL OF MEDICINAL CHEMISTRY (2016)
Stabilin-1 and Stabilin-2 are specific receptors for the cellular internalization of phosphorothioate-modified antisense oligonucleotides (ASOs) in the liver
Colton M. Miller et al.
NUCLEIC ACIDS RESEARCH (2016)
Pharmacokinetics, biodistribution and cell uptake of antisense oligonucleotides
Richard S. Geary et al.
ADVANCED DRUG DELIVERY REVIEWS (2015)
Efficient Synthesis and Biological Evaluation of 5′-GalNAc Conjugated Antisense Oligonucleotides
Michael E. Ostergaard et al.
BIOCONJUGATE CHEMISTRY (2015)
Identification and Characterization of GLP-1 Receptor-Expressing Cells Using a New Transgenic Mouse Model
Paul Richards et al.
DIABETES (2014)
GLP-1 Receptor Localization in Monkey and Human Tissue: Novel Distribution Revealed With Extensively Validated Monoclonal Antibody
Charles Pyke et al.
ENDOCRINOLOGY (2014)
Real-time trafficking and signaling of the glucagon-like peptide-1 receptor
Sarah Noerklit Roed et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2014)
Targeted delivery of antisense oligonucleotides to hepatocytes using triantennary N-acetyl galactosamine improves potency 10-fold in mice
Thazha P. Prakash et al.
NUCLEIC ACIDS RESEARCH (2014)
GLP-1 Receptor Activation Indirectly Reduces Hepatic Lipid Accumulation But Does Not Attenuate Development of Atherosclerosis in Diabetic Male ApoE(-/-) Mice
Naim Panjwani et al.
ENDOCRINOLOGY (2013)
Receptors, endocytosis, and trafficking: the biological basis of targeted delivery of antisense and siRNA oligonucleotides
R. L. Juliano et al.
JOURNAL OF DRUG TARGETING (2013)
Characterization of Target mRNA Reduction Through In Situ RNA Hybridization in Multiple Organ Systems Following Systemic Antisense Treatment in Animals
Gene Hung et al.
NUCLEIC ACID THERAPEUTICS (2013)
Targeted estrogen delivery reverses the metabolic syndrome
Brian Finan et al.
NATURE MEDICINE (2012)
Intracellular delivery of an antisense oligonucleotide via endocytosis of a G protein-coupled receptor
Xin Ming et al.
NUCLEIC ACIDS RESEARCH (2010)
No mantle formation in rodent islets-The prototype of islet revisited
Michael Kharouta et al.
DIABETES RESEARCH AND CLINICAL PRACTICE (2009)
Trafficking of G protein-coupled receptors
Matthew T. Drake et al.
CIRCULATION RESEARCH (2006)
The influence of GLP-1 on glucose-stimulated insulin secretion -: Effects on β-cell sensitivity in type 2 and nondiabetic subjects
LL Kjems et al.
DIABETES (2003)