期刊
CARDIOVASCULAR ENGINEERING AND TECHNOLOGY
卷 9, 期 4, 页码 641-653出版社
SPRINGER
DOI: 10.1007/s13239-018-00390-2
关键词
Inferior vena cava; Hemodynamics; Particle image velocimetry; Verification and validation
资金
- FDA Critical Path Initiative [HHSF223201610405P]
- Penn State College of Engineering Instrumentation Grant
- Department of Health and Human Services
Purpose-Although many previous computational fluid dynamics (CFD) studies have investigated the hemodynamics in the inferior vena cava (IVC), few studies have compared computational predictions to experimental data, and only qualitative comparisons have been made. Herein, we provide particle image velocimetry (PIV) measurements of flow in a patient-averaged IVC geometry under idealized conditions typical of those used in the preclinical evaluation of IVC filters. Methods-Measurements are acquired under rest and exercise flow rate conditions in an optically transparent model fabricated using 3D printing. To ensure that boundary conditions are well-defined and to make follow-on CFD validation studies more convenient, fully-developed flow is provided at the inlets (i.e., the iliac veins) by extending them with straight rigid tubing longer than the estimated entrance lengths. Velocity measurements are then obtained at the downstream end of the tubing to confirm Poiseuille inflow boundary conditions. Results-Measurements in the infrarenal IVC reveal that flow profiles are blunter in the sagittal plane (minor axis) than in the coronal plane (major axis). Peak in-plane velocity magnitudes are 4.9cm/s and 27cm/s under the rest and exercise conditions, respectively. Flow profiles are less parabolic and exhibit more inflection points at the higher flow rate. Bimodal velocity peaks are also observed in the sagittal plane at the elevated flow condition. Conclusions-The IVC geometry, boundary conditions, and infrarenal velocity measurements are provided for download on a free and publicly accessible repositoryat 10.6084/m9.figshare.7198703. These data will facilitate future CFD validation studies of idealized, in vitro IVC hemodynamics and of similar laminar flows in vascular geometries.
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