期刊
BIOCHIMIE
卷 117, 期 -, 页码 110-118出版社
ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
DOI: 10.1016/j.biochi.2014.11.019
关键词
Escherichia coli; Ribosome; rRNA; Modification; RNA methyltransferase; Ribosome assembly
资金
- RFBR [13-04-00836, 13-04-40211, 14-04-01061]
- RSF [14-24-00061]
- Russian Science Foundation [14-24-00061] Funding Source: Russian Science Foundation
A ribosome is a ribonucleoprotein that performs the synthesis of proteins. Ribosomal RNA of all organisms includes a number of modified nucleotides, such as base or ribose methylated and pseudouridines. Methylated nucleotides are highly conserved in bacteria and some even universally. In this review we discuss available data on a set of modification sites in the most studied bacteria, Escherichia coli. While most rRNA modification enzymes are known for this organism, the function of the modified nucleotides is rarely identified. (C) 2014 Elsevier B.V. and Societe francaise de biochimie et biologie Moleculaire (SFBBM). All rights reserved.
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