期刊
ADVANCED DRUG DELIVERY REVIEWS
卷 105, 期 -, 页码 228-241出版社
ELSEVIER
DOI: 10.1016/j.addr.2016.05.015
关键词
Nano-graphene; Drug delivery; Stimuli-responsive; Cancer therapy
资金
- National Basic Research Program of China (973 Program) [2014CB931900]
- National Natural Science Foundation of China [81471716, 31400861]
- National Natural Science Foundation of Jiangsu Province [BK20140320]
- Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD)
Nano-graphene as a class of two-dimensional sp(2) carbon nanomaterial has attracted tremendous attentions in various fields in the past decade. Utilizing its unique physical and chemical properties, nano-graphene has also shown great promises in the area of biomedicine, for application in biosensing, imaging and therapy. In particular, with all atoms exposed on its surface, nano-graphene exhibits ultra-high surface area available for efficient binding/loading of various biomolecules of interests, and has been widely used as multifunctional nano-carriers for drug and gene delivery. In this review article, we will summarize the recent advances in the development of nano-graphene as stimuli-responsive nano-carriers for drug delivery, as well as the applications of these smart systems for cancer therapy. (C) 2016 Elsevier B.V. All rights reserved.
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