期刊
ADVANCED DRUG DELIVERY REVIEWS
卷 105, 期 -, 页码 3-19出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.addr.2016.04.005
关键词
Molecular diagnostics; Nucleic acid tests; PCR; Hybridization; Next-generation sequencing
资金
- Cancer Prevention Research Institute of Texas (CPRIT) award [RP140132]
Nucleic acid sequence variations have been implicated in many diseases, and reliable detection and quantitation of DNA/RNA biomarkers can inform effective therapeutic action, enabling precision medicine. Nucleic acid analysis technologies being translated into the clinic can broadly be classified into hybridization, PCR, and sequencing, as well as their combinations. Here we review the molecular mechanisms of popular commercial assays, and their progress in translation into in vitro diagnostics. (C) 2016 The Authors. Published by Elsevier B.V.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据