相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Novel and shared neoantigen derived from histone 3 variant H3.3K27M mutation for glioma T cell therapy
Zinal S. Chheda et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2018)
Trivalent CAR T cells overcome interpatient antigenic variability in glioblastoma
Kevin Bielamowicz et al.
NEURO-ONCOLOGY (2018)
Is the blood-brain barrier really disrupted in all glioblastomas? A critical assessment of existing clinical data
Jann N. Sarkaria et al.
NEURO-ONCOLOGY (2018)
CD70, a novel target of CAR T-cell therapy for gliomas
Linchun Jin et al.
NEURO-ONCOLOGY (2018)
Nivolumab with or without ipilimumab in patients with recurrent glioblastoma: results from exploratory phase I cohorts of CheckMate 143
Antonio Omuro et al.
NEURO-ONCOLOGY (2018)
High-Affinity GD2-Specific CAR T Cells Induce Fatal Encephalitis in a Preclinical Neuroblastoma Model
Sarah A. Richman et al.
CANCER IMMUNOLOGY RESEARCH (2018)
Glycogen synthase kinase 3 inhibition lowers PD-1 expression, promotes long-term survival and memory generation in antigen-specific CAR-T cells
Sadhak Sengupta et al.
CANCER LETTERS (2018)
Optimization of IL13Rα2-Targeted Chimeric Antigen Receptor T Cells for Improved Anti-tumor Efficacy against Glioblastoma
Christine E. Brown et al.
MOLECULAR THERAPY (2018)
Potent antitumor efficacy of anti-GD2 CAR T cells in H3-K27M+ diffuse midline gliomas
Christopher W. Mount et al.
NATURE MEDICINE (2018)
Development of third generation anti-EGFRvIII chimeric T cells and EGFRvIII-\-expressing artificial antigen presenting cells for adoptive cell therapy for glioma
Ayguen Sahin et al.
PLOS ONE (2018)
Constitutive and TNFα-inducible expression of chondroitin sulfate proteoglycan 4 in glioblastoma and neurospheres: Implications for CAR-T cell therapy
Serena Pellegatta et al.
SCIENCE TRANSLATIONAL MEDICINE (2018)
CAR-T cells: the long and winding road to solid tumors
Maria Michela D'Aloia et al.
CELL DEATH & DISEASE (2018)
Advances in Radiotherapy for Glioblastoma
Justin Mann et al.
FRONTIERS IN NEUROLOGY (2018)
Temozolomide lymphodepletion enhances CAR abundance and correlates with antitumor efficacy against established glioblastoma
Carter M. Suryadevara et al.
ONCOIMMUNOLOGY (2018)
Immune evasion mediated by PD-L1 on glioblastoma-derived extracellular vesicles
Franz L. Ricklefs et al.
SCIENCE ADVANCES (2018)
Combined Nivolumab and Ipilimumab in Melanoma Metastatic to the Brain
Hussein A. Tawbi et al.
NEW ENGLAND JOURNAL OF MEDICINE (2018)
NKG2D-Based CAR T Cells and Radiotherapy Exert Synergistic Efficacy in Glioblastoma
Tobias Weiss et al.
CANCER RESEARCH (2018)
Pediatric high-grade glioma: biologically and clinically in need of new thinking
Chris Jones et al.
NEURO-ONCOLOGY (2017)
Mutant IDH1 regulates the tumor-associated immune system in gliomas
Nduka M. Amankulor et al.
GENES & DEVELOPMENT (2017)
Tumor associated CD70 expression is involved in promoting tumor migration and macrophage infiltration in GBM
Haitao Ge et al.
INTERNATIONAL JOURNAL OF CANCER (2017)
Isocitrate dehydrogenase mutations suppress STAT1 and CD8+ T cell accumulation in gliomase
Gary Kohanbash et al.
JOURNAL OF CLINICAL INVESTIGATION (2017)
The brain-penetrating CXCR4 antagonist, PRX177561, increases the antitumor effects of bevacizumab and sunitinib in preclinical models of human glioblastoma
Giovanni Luca Gravina et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2017)
Serial changes in lymphocyte subsets in patients with newly diagnosed high grade astrocytomas treated with standard radiation and temozolomide
Jian L. Campian et al.
JOURNAL OF NEURO-ONCOLOGY (2017)
The Flipside of the Power of Engineered T Cells: Observed and Potential Toxicities of Genetically Modified T Cells as Therapy
Felipe Bedoya et al.
MOLECULAR THERAPY (2017)
Radiotherapy and immunotherapy: a beneficial liaison?
Ralph R. Weichselbaum et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2017)
Correlation of immune phenotype with IDH mutation in diffuse glioma
Anna Sophie Berghoff et al.
NEURO-ONCOLOGY (2017)
RANDOMIZED PHASE 3 STUDY EVALUATING THE EFFICACY AND SAFETY OF NIVOLUMAB VS BEVACIZUMAB IN PATIENTS WITH RECURRENT GLIOBLASTOMA: CHECKMATE 143
D. A. Reardona et al.
NEURO-ONCOLOGY (2017)
Targeting Neoantigens in Glioblastoma: An Overview of Cancer Immunogenomics and Translational Implications
Tanner M. Johanns et al.
NEUROSURGERY (2017)
Detection of immune responses after immunotherapy in glioblastoma using PET and MRI
Joseph P. Antonios et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Dual role of ALCAM in neuroinflammation and blood-brain barrier homeostasis
Marc-Andre Lecuyer et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
A single dose of peripherally infused EGFRvIII-directed CAR T cells mediates antigen loss and induces adaptive resistance in patients with recurrent glioblastoma
Donald M. O'Rourke et al.
SCIENCE TRANSLATIONAL MEDICINE (2017)
The novel CXCR4 antagonist, PRX177561, reduces tumor cell proliferation and accelerates cancer stem cell differentiation in glioblastoma preclinical models
Giovanni Luca Gravina et al.
TUMOR BIOLOGY (2017)
Interleukin-13 receptor alpha 2 cooperates with EGFRvIII signaling to promote glioblastoma multiforme
Jennifer P. Newman et al.
NATURE COMMUNICATIONS (2017)
Endothelial Activation and Blood-Brain Barrier Disruption in Neurotoxicity after Adoptive Immunotherapy with CD19 CAR-T Cells
Juliane Gust et al.
CANCER DISCOVERY (2017)
Transgenic Expression of IL15 Improves Antiglioma Activity of IL13Rα2-CAR T Cells but Results in Antigen Loss Variants
Giedre Krenciute et al.
CANCER IMMUNOLOGY RESEARCH (2017)
MRI in Glioma Immunotherapy: Evidence, Pitfalls, and Perspectives
Domenico Aquino et al.
JOURNAL OF IMMUNOLOGY RESEARCH (2017)
Antigen Loss variants: catching Hold of escaping Foes
Maulik Vyas et al.
FRONTIERS IN IMMUNOLOGY (2017)
HER2-Specific Chimeric Antigen Receptor-Modified Virus-Specific T Cells for Progressive Glioblastoma A Phase 1 Dose-Escalation Trial
Nabil Ahmed et al.
JAMA ONCOLOGY (2017)
Cellular and Molecular Identity of Tumor-Associated Macrophages in Glioblastoma
Zhihong Chen et al.
CANCER RESEARCH (2017)
The network of immunosuppressive pathways in glioblastoma
Davide Mangani et al.
BIOCHEMICAL PHARMACOLOGY (2017)
The Microenvironmental Landscape of Brain Tumors
Daniela F. Quail et al.
CANCER CELL (2017)
The movers and shapers in immune privilege of the CNS
Britta Engelhardt et al.
NATURE IMMUNOLOGY (2017)
Late Pseudoprogression in Glioblastoma: Diagnostic Value of Dynamic O-(2-[18F]fluoroethyl)-L-Tyrosine PET
Sied Kebir et al.
CLINICAL CANCER RESEARCH (2016)
PD-L1 expression and prognostic impact in glioblastoma
Edjah K. Nduom et al.
NEURO-ONCOLOGY (2016)
Design of Switchable Chimeric Antigen Receptor T Cells Targeting Breast Cancer
Yu Cao et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2016)
Precision Tumor Recognition by T Cells With Combinatorial Antigen-Sensing Circuits
Kole T. Roybal et al.
CELL (2016)
Engineering Customized Cell Sensing and Response Behaviors Using Synthetic Notch Receptors
Leonardo Morsut et al.
CELL (2016)
Human CAR T cells with cell-intrinsic PD-1 checkpoint blockade resist tumor-mediated inhibition
Leonid Cherkassky et al.
JOURNAL OF CLINICAL INVESTIGATION (2016)
Tandem CAR T cells targeting HER2 and IL13Rα2 mitigate tumor antigen escape (Publication with Expression of Concern. See vol. 129, pg. 3464, 2019)
Meenakshi Hegde et al.
JOURNAL OF CLINICAL INVESTIGATION (2016)
Characterization and Functional Analysis of scFv-based Chimeric Antigen Receptors to Redirect T Cells to IL13Rα2-positive Glioma
Giedre Krenciute et al.
MOLECULAR THERAPY (2016)
A Phase II randomized study of galunisertib monotherapy or galunisertib plus lomustine compared with lomustine monotherapy in patients with recurrent glioblastoma
Alba A. Brandes et al.
NEURO-ONCOLOGY (2016)
Regression of Glioblastoma after Chimeric Antigen Receptor T-Cell Therapy
Christine E. Brown et al.
NEW ENGLAND JOURNAL OF MEDICINE (2016)
Versatile strategy for controlling the specificity and activity of engineered T cells
Jennifer S. Y. Ma et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Switch-mediated activation and retargeting of CAR-T cells for B-cell malignancies
David T. Rodgers et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Epigenetic stability of exhausted T cells limits durability of reinvigoration by PD-1 blockade
Kristen E. Pauken et al.
SCIENCE (2016)
The Nature of Myeloid-Derived Suppressor Cells in the Tumor Microenvironment
Vinit Kumar et al.
TRENDS IN IMMUNOLOGY (2016)
GBM heterogeneity as a function of variable epidermal growth factor receptor variant III activity
Olle R. Lindberg et al.
ONCOTARGET (2016)
Endogenous Neoantigen-Specific CD8 T Cells Identified in Two Glioblastoma Models Using a Cancer Immunogenomics Approach
Tanner M. Johanns et al.
CANCER IMMUNOLOGY RESEARCH (2016)
CAR models: next-generation CAR modifications for enhanced T-cell function
Daniel Abate-Daga et al.
MOLECULAR THERAPY-ONCOLYTICS (2016)
Chimeric antigen receptor T-cell therapy for solid tumors
Kheng Newick et al.
MOLECULAR THERAPY-ONCOLYTICS (2016)
Glioblastoma: Overview of Disease and Treatment
Mary Elizabeth Davis
CLINICAL JOURNAL OF ONCOLOGY NURSING (2016)
Inducible caspase-9 suicide gene controls adverse effects from alloreplete T cells after haploidentical stem cell transplantation
Xiaoou Zhou et al.
BLOOD (2015)
HLA class I is most tightly linked to levels of tapasin compared with other antigen-processing proteins in glioblastoma
Camilla Thuring et al.
BRITISH JOURNAL OF CANCER (2015)
Lenalidomide enhances the function of chimeric antigen receptor T cells against the epidermal growth factor receptor variant III by enhancing immune synapses
S. Kuramitsu et al.
CANCER GENE THERAPY (2015)
Bioactivity and Safety of IL13Rα2-Redirected Chimeric Antigen Receptor CD8+ T Cells in Patients with Recurrent Glioblastoma
Christine E. Brown et al.
CLINICAL CANCER RESEARCH (2015)
Central nervous system infiltrates are characterized by features of ongoing B cell-related immune activity in MP4-induced experimental autoimmune encephalomyelitis
Helena Batoulis et al.
CLINICAL IMMUNOLOGY (2015)
A dural lymphatic vascular system that drains brain interstitial fluid and macromolecules
Aleksanteri Aspelund et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2015)
Focused ultrasound-induced blood-brain barrier opening to enhance interleukin-12 delivery for brain tumor immunotherapy: a preclinical feasibility study
Pin-Yuan Chen et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2015)
T cells expressing CD19 chimeric antigen receptors for acute lymphoblastic leukaemia in children and young adults: a phase 1 dose-escalation trial
Daniel W. Lee et al.
LANCET (2015)
Immunotherapy response assessment in neuro-oncology: a report of the RANO working group
Hideho Okada et al.
LANCET ONCOLOGY (2015)
Rational development and characterization of humanized anti-EGFR variant III chimeric antigen receptor T cells for glioblastoma
Laura A. Johnson et al.
SCIENCE TRANSLATIONAL MEDICINE (2015)
Non-redundant requirement for CXCR3 signalling during tumoricidal T-cell trafficking across tumour vascular checkpoints
M. E. Mikucki et al.
NATURE COMMUNICATIONS (2015)
Pitfalls in le neuroimaging of glioblastoma in le era of antiangiogenic and immuno/targeted therapy - detecting illusive disease, defining response
Raymond Y. Huang et al.
FRONTIERS IN NEUROLOGY (2015)
Programmed death ligand 1 expression and tumor-infiltrating lymphocytes in glioblastoma
Anna Sophie Berghoff et al.
NEURO-ONCOLOGY (2015)
Transforming growth factor-beta and its implication in the malignancy of gliomas
Laurent-Olivier Roy et al.
TARGETED ONCOLOGY (2015)
Enhancement of T cell recruitment and infiltration into tumours
C. Oelkrug et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2014)
EGFRvIII mCAR-Modified T-Cell Therapy Cures Mice with Established Intracerebral Glioma and Generates Host Immunity against Tumor-Antigen Loss
John H. Sampson et al.
CLINICAL CANCER RESEARCH (2014)
Multifactorial T-cell Hypofunction That Is Reversible Can Limit the Efficacy of Chimeric Antigen Receptor-Transduced Human T cells in Solid Tumors
Edmund K. Moon et al.
CLINICAL CANCER RESEARCH (2014)
T cells redirected to interleukin-13Rα2 with interleukin-13 mutein-chimeric antigen receptors have anti-glioma activity but also recognize interleukin-13Rα1
Simone Krebs et al.
CYTOTHERAPY (2014)
Neo-antigens predicted by tumor genome meta-analysis correlate with increased patient survival
Scott D. Brown et al.
GENOME RESEARCH (2014)
The role of CXCR4 in highly malignant human gliomas biology: Current knowledge and future directions
Filippo Gagliardi et al.
GLIA (2014)
Intracerebral delivery of a third generation EGFRvIII-specific chimeric antigen receptor is efficacious against human glioma
Bryan D. Choi et al.
JOURNAL OF CLINICAL NEUROSCIENCE (2014)
Chimeric Antigen Receptor T Cells for Sustained Remissions in Leukemia
Shannon L. Maude et al.
NEW ENGLAND JOURNAL OF MEDICINE (2014)
EGFRvIII-Specific Chimeric Antigen Receptor T Cells Migrate to and Kill Tumor Deposits Infiltrating the Brain Parenchyma in an Invasive Xenograft Model of Glioblastoma
Hongsheng Miao et al.
PLOS ONE (2014)
Fractionated radiotherapy is the main stimulus for the induction of cell death and of Hsp70 release of p53 mutated glioblastoma cell lines
Yvonne Rubner et al.
RADIATION ONCOLOGY (2014)
Regional delivery of mesothelin-targeted CAR T cell therapy generates potent and long-lasting CD4-dependent tumor immunity
Prasad S. Adusumilli et al.
SCIENCE TRANSLATIONAL MEDICINE (2014)
Chemokines in the balance: maintenance of homeostasis and protection at CNS barriers
Jessica L. Williams et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2014)
Disruption of astrocyte-vascular coupling and the blood-brain barrier by invading glioma cells
Stacey Watkins et al.
NATURE COMMUNICATIONS (2014)
Effects of Single or Combined Treatments with Radiation and Chemotherapy on Survival and Danger Signals Expression in Glioblastoma Cell Lines
Francesca Pasi et al.
BIOMED RESEARCH INTERNATIONAL (2014)
STING Contributes to Antiglioma Immunity via Triggering Type I IFN Signals in the Tumor Microenvironment
Takayuki Ohkuri et al.
CANCER IMMUNOLOGY RESEARCH (2014)
Leveraging chemotherapy-induced lymphopenia to potentiate cancer immunotherapy
Luis Sanchez-Perez et al.
ONCOIMMUNOLOGY (2014)
Sustained CD4+ T cell-driven lymphopenia without a compensatory IL-7/IL-15 response among high-grade glioma patients treated with radiation and temozolomide
Susannah Ellsworth et al.
ONCOIMMUNOLOGY (2014)
Unique genetic and epigenetic mechanisms driving paediatric diffuse high-grade glioma
Chris Jones et al.
NATURE REVIEWS CANCER (2014)
A new look at cerebrospinal fluid circulation
Thomas Brinker et al.
FLUIDS AND BARRIERS OF THE CNS (2014)
Phase I trial of a multi-epitope-pulsed dendritic cell vaccine for patients with newly diagnosed glioblastoma
Surasak Phuphanich et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2013)
The Etiology of Treatment-related Lymphopenia in Patients with Malignant Gliomas: Modeling Radiation Dose to Circulating Lymphocytes Explains Clinical Observations and Suggests Methods of Modifying the Impact of Radiation on Immune Cells
Susannah Yovino et al.
CANCER INVESTIGATION (2013)
The Somatic Genomic Landscape of Glioblastoma
Cameron W. Brennan et al.
CELL (2013)
LOH in the HLA Class I Region at 6p21 Is Associated with Shorter Survival in Newly Diagnosed Adult Glioblastoma
Jacky T. Yeung et al.
CLINICAL CANCER RESEARCH (2013)
Chimeric antigen receptor containing ICOS signaling domain mediates specific and efficient antitumor effect of T cells against EGFRvIII expressing glioma
Chan-Juan Shen et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2013)
Cancer Regression and Neurological Toxicity Following Anti-MAGE-A3 TCR Gene Therapy
Richard A. Morgan et al.
JOURNAL OF IMMUNOTHERAPY (2013)
Combinational Targeting Offsets Antigen Escape and Enhances Effector Functions of Adoptively Transferred T Cells in Glioblastoma
Meenakshi Hegde et al.
MOLECULAR THERAPY (2013)
T Cells Redirected to EphA2 for the Immunotherapy of Glioblastoma
Kevin K. H. Chow et al.
MOLECULAR THERAPY (2013)
EGFRvIII gene rearrangement is an early event in glioblastoma tumorigenesis and expression defines a hierarchy modulated by epigenetic mechanisms
C. A. Del Vecchio et al.
ONCOGENE (2013)
Expression and Functional Heterogeneity of Chemokine Receptors CXCR4 and CXCR7 in Primary Patient-Derived Glioblastoma Cells
Che Liu et al.
PLOS ONE (2013)
PD-1-and CTLA-4-Based Inhibitory Chimeric Antigen Receptors (iCARs) Divert Off-Target Immunotherapy Responses
Victor D. Fedorov et al.
SCIENCE TRANSLATIONAL MEDICINE (2013)
TanCAR: A Novel Bispecific Chimeric Antigen Receptor for Cancer Immunotherapy
Zakaria Grada et al.
MOLECULAR THERAPY-NUCLEIC ACIDS (2013)
Expression of miR-17-92 enhances anti-tumor activity of T-cells transduced with the anti-EGFRvIII chimeric antigen receptor in mice bearing human GBM xenografts
Masasuke Ohno et al.
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2013)
K27M mutation in histone H3.3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas
Dong-Anh Khuong-Quang et al.
ACTA NEUROPATHOLOGICA (2012)
Molecular pathogenesis of IDH mutations in gliomas
Koichi Ichimura
BRAIN TUMOR PATHOLOGY (2012)
PD-1 Blockade Enhances T-cell Migration to Tumors by Elevating IFN-γ Inducible Chemokines
Weiyi Peng et al.
CANCER RESEARCH (2012)
Ultrasound-Induced Blood-Brain Barrier Opening
Elisa E. Konofagou et al.
CURRENT PHARMACEUTICAL BIOTECHNOLOGY (2012)
Migration of monocytes after intracerebral injection at entorhinal cortex lesion site
Miriam Kaminski et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2012)
Capture, crawl, cross: the T cell code to breach the blood-brain barriers
Britta Engelhardt et al.
TRENDS IN IMMUNOLOGY (2012)
T-cell production of matrix metalloproteinases and inhibition of parasite clearance by TIMP-1 during chronic Toxoplasma infection in the brain
Robin T. Clark et al.
ASN NEURO (2011)
COX-2 Blockade Suppresses Gliomagenesis by Inhibiting Myeloid-Derived Suppressor Cells
Mitsugu Fujita et al.
CANCER RESEARCH (2011)
CTLA4 Blockade Induces Frequent Tumor Infiltration by Activated Lymphocytes Regardless of Clinical Responses in Humans
Rong Rong Huang et al.
CLINICAL CANCER RESEARCH (2011)
Induction of CD8+ T-Cell Responses Against Novel Glioma-Associated Antigen Peptides and Clinical Activity by Vaccinations With α-Type 1 Polarized Dendritic Cells and Polyinosinic-Polycytidylic Acid Stabilized by Lysine and Carboxymethylcellulose in Patients With Recurrent Malignant Glioma
Hideho Okada et al.
JOURNAL OF CLINICAL ONCOLOGY (2011)
MR perfusion and diffusion imaging in the follow-up of recurrent glioblastoma treated with dendritic cell immunotherapy: a pilot study
Matej Vrabec et al.
NEURORADIOLOGY (2011)
Inducible Apoptosis as a Safety Switch for Adoptive Cell Therapy
Antonio Di Stasi et al.
NEW ENGLAND JOURNAL OF MEDICINE (2011)
Targeting the NG2/CSPG4 Proteoglycan Retards Tumour Growth and Angiogenesis in Preclinical Models of GBM and Melanoma
Jian Wang et al.
PLOS ONE (2011)
Development of an EGFRvIII specific recombinant antibody
Puja Gupta et al.
BMC BIOTECHNOLOGY (2010)
Poly-ICLC promotes the infiltration of effector T cells into intracranial gliomas via induction of CXCL10 in IFN-α and IFN-γ dependent manners
Xinmei Zhu et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2010)
Tumor-Specific CD8+ T Cells Expressing Interleukin-12 Eradicate Established Cancers in Lymphodepleted Hosts
Sid P. Kerkar et al.
CANCER RESEARCH (2010)
HER2-Specific T Cells Target Primary Glioblastoma Stem Cells and Induce Regression of Autologous Experimental Tumors
Nabil Ahmed et al.
CLINICAL CANCER RESEARCH (2010)
Differentiation and Persistence of Memory CD8+ T Cells Depend on T Cell Factor 1
Xinyuan Zhou et al.
IMMUNITY (2010)
Trafficking of immune cells in the central nervous system
Emma H. Wilson et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
Vaccine provides new hope for patients with deadly brain cancer
[Anonymous]
FUTURE NEUROLOGY (2010)
Naive tumor-specific CD4+ T cells differentiated in vivo eradicate established melanoma
Ying Xie et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2010)
Soluble CD70: a novel immunotherapeutic agent for experimental glioblastoma Laboratory investigation
James Miller et al.
JOURNAL OF NEUROSURGERY (2010)
Glioblastoma Cancer-Initiating Cells Inhibit T-Cell Proliferation and Effector Responses by the Signal Transducers and Activators of Transcription 3 Pathway
Jun Wei et al.
MOLECULAR CANCER THERAPEUTICS (2010)
Case Report of a Serious Adverse Event Following the Administration of T Cells Transduced With a Chimeric Antigen Receptor Recognizing ERBB2
Richard A. Morgan et al.
MOLECULAR THERAPY (2010)
Systemic immune suppression in glioblastoma: the interplay between CD14+HLA-DRlo/neg monocytes, tumor factors, and dexamethasone
Michael P. Gustafson et al.
NEURO-ONCOLOGY (2010)
Immunologic Escape After Prolonged Progression-Free Survival With Epidermal Growth Factor Receptor Variant III Peptide Vaccination in Patients With Newly Diagnosed Glioblastoma
John H. Sampson et al.
JOURNAL OF CLINICAL ONCOLOGY (2010)
Brain Tumor Immunotherapy with Type-1 Polarizing Strategies
Hideho Okada
CANCER VACCINES (2009)
Systemic Inhibition of Transforming Growth Factor-β in Glioma-Bearing Mice Improves the Therapeutic Efficacy of Glioma-Associated Antigen Peptide Vaccines
Ryo Ueda et al.
CLINICAL CANCER RESEARCH (2009)
Autologous MUC1-specific Th1 effector cell immunotherapy induces differential levels of systemic TReg cell subpopulations that result in increased ovarian cancer patient survival
Mark J. Dobrzanski et al.
CLINICAL IMMUNOLOGY (2009)
Tumor Burden Influences Cytotoxic T Cell Development in Metastatic Breast Cancer Patients-A Phase I/II Study
Stephen E. Wright et al.
IMMUNOLOGICAL INVESTIGATIONS (2009)
Identification of O-glycosylated decapeptides within the MUC1 repeat domain as potential MHC class I (A2) binding epitopes
Tanja Ninkovic et al.
MOLECULAR IMMUNOLOGY (2009)
Wnt signaling arrests effector T cell differentiation and generates CD8+ memory stem cells
Luca Gattinoni et al.
NATURE MEDICINE (2009)
Noninvasive detection of therapeutic cytolytic T cells with F-18-FHBG PET in a patient with glioma
Shahriar S. Yaghoubi et al.
NATURE CLINICAL PRACTICE ONCOLOGY (2009)
PD-1 and its ligands in tolerance and immunity
Mary E. Keir et al.
ANNUAL REVIEW OF IMMUNOLOGY (2008)
Mucin-type O-glycosylation and its potential use in drug and vaccine development
Mads Agervig Tarp et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2008)
Vaccination elicits correlated immune and clinical responses in glioblastoma multiforme patients
Christopher J. Wheeler et al.
CANCER RESEARCH (2008)
Antitumor activity of EBV-specific T lymphocytes transduced with a dominant negative TGF-β receptor
Aaron E. Foster et al.
JOURNAL OF IMMUNOTHERAPY (2008)
Solutes, but not cells, drain from the brain parenchyma along basement membranes of capillaries and arteries: significance for cerebral amyloid angiopathy and neuroimmunology
R. O. Carare et al.
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY (2008)
CXCR4 expression is elevated in glioblastoma multiforme and correlates with an increase in intensity and extent of peritumoral T2-weighted magnetic resonance imaging signal abnormalities
Charles B. Stevenson et al.
NEUROSURGERY (2008)
CXCR4 antagonism increases T cell trafficking in the central nervous system and improves survival from West Nile virus encephalitis
Erin E. McCandless et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Mechanisms of disease: temozolomide and glioblastoma - look to the future
Maciej M. Mrugala et al.
NATURE CLINICAL PRACTICE ONCOLOGY (2008)
Activated leukocyte cell adhesion molecule promotes leukocyte trafficking into the central nervous system
Romain Cayrol et al.
NATURE IMMUNOLOGY (2008)
A novel small molecule inhibitor of signal transducers and activators of transcription 3 reverses immune tolerance in malignant glioma patients
S. Farzana Hussain et al.
CANCER RESEARCH (2007)
An antigen-specific pathway for CD8 T cells across the blood-brain barrier
Ian Galea et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2007)
Tumor-derived chemokine MCP-1/CCL2 is sufficient for mediating tumor tropism of adoptively transferred T cells
Christine E. Brown et al.
JOURNAL OF IMMUNOLOGY (2007)
CD4 cells can be more efficient at tumor rejection than CD8 cells
Ainhoa Perez-Diez et al.
BLOOD (2007)
Unrestrained glycogen synthase kinase-3β activity leads to activated T cell death and can be inhibited by natural adjuvant
Sadhak Sengupta et al.
JOURNAL OF IMMUNOLOGY (2007)
Antigenic profiling of glioma cells to generate allogeneic vaccines or dendritic cell-based therapeutics
Jian Gang Zhang et al.
CLINICAL CANCER RESEARCH (2007)
Intercellular adhesion molecule-1 expression is required on multiple cell types for the development of experimental autoimmune encephalomyelitis
Daniel C. Bullard et al.
JOURNAL OF IMMUNOLOGY (2007)
Crosstalk between cancer and immune cells: role of STAT3 in the tumour microenvironment
Hua Yu et al.
NATURE REVIEWS IMMUNOLOGY (2007)
A genome-wide screen reveals functional gene clusters in the cancer genome and identifies EphA2 as a mitogen in glioblastoma
Fenghua Liu et al.
CANCER RESEARCH (2006)
The combination of ionizing radiation and peripheral vaccination produces long-term survival of mice bearing established invasive GL261 gliomas
Elizabeth W. Newcomb et al.
CLINICAL CANCER RESEARCH (2006)
Adoptive transfer of type 1 CTL mediates effective anti-central nervous system tumor response: Critical roles of IFN-inducible protein-10
F Nishimura et al.
CANCER RESEARCH (2006)
Extracorporeal high intensity focused ultrasound in the treatment of patients with solid malignancy
F Wu
MINIMALLY INVASIVE THERAPY & ALLIED TECHNOLOGIES (2006)
IL-13 signaling through the IL-13 alpha 2 receptor is involved in induction of TGF-beta 1 production and fibrosis
S Fichtner-Feigl et al.
NATURE MEDICINE (2006)
Human leukocyte antigen and antigen processing machinery component defects in astrocytic tumors
A Facoetti et al.
CLINICAL CANCER RESEARCH (2005)
High-intensity focused ultrasound in the treatment of solid tumours
JE Kennedy
NATURE REVIEWS CANCER (2005)
Technology insight:: high-intensity focused ultrasound for urologic cancers
C Chaussy et al.
NATURE CLINICAL PRACTICE UROLOGY (2005)
Brain pericytes contribute to the induction and up-regulation of blood-brain barrier functions through transforming growth factor-β production
S Dohgu et al.
BRAIN RESEARCH (2005)
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
R Stupp et al.
NEW ENGLAND JOURNAL OF MEDICINE (2005)
IL-6 is required for glioma development in a mouse model
J Weissenberger et al.
ONCOGENE (2004)
Specific recognition and killing of glioblastoma multiforme by interleukin 13-zetakine redirected cytolytic T cells
KS Kahlon et al.
CANCER RESEARCH (2004)
HER-2, gp100, and MAGE-1 are expressed in human glioblastoma and recognized by cytotoxic T cells
G Liu et al.
CANCER RESEARCH (2004)
A small-molecule antagonist of CXCR4 inhibits intracranial growth of primary brain tumors
JB Rubin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Adapting a transforming growth factor β-related tumor protection strategy to enhance antitumor immunity
CM Bollard et al.
BLOOD (2002)
High-intensity focused ultrasound selectively disrupts the blood-brain barrier in vivo
AH Mesiwala et al.
ULTRASOUND IN MEDICINE AND BIOLOGY (2002)
The quantity of naturally processed peptides stably bound by HLA-A*0201 is significantly reduced in the absence of tapasin
LD Barber et al.
TISSUE ANTIGENS (2001)
Tapasin: an ER chaperone that controls MHC class I assembly with peptide
AG Grandea et al.
TRENDS IN IMMUNOLOGY (2001)
Negative regulation of T cell proliferation and interleukin 2 production by the serine threonine kinase GSK-3
T Ohteki et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2000)
Consequences of cell death: Exposure to necrotic tumor cells, but not primary tissue cells or apoptotic cells, induces the maturation of immunostimulatory dendritic cells
B Sauter et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2000)