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CARDIOVASCULAR RESEARCH (2006)
The G protein-coupled receptor kinase-2 is a TGFβ-inducible antagonist of TGFβ signal transduction
J Ho et al.
EMBO JOURNAL (2005)
A crucial role for GRK2 in regulation of endothelial cell nitric oxide synthase function in portal hypertension
SL Liu et al.
NATURE MEDICINE (2005)
Vascular smooth muscle overexpression of G protein-coupled receptor kinase 5 elevates blood pressure, which segregates with sex and is dependent on Gi-mediated signaling
JR Keys et al.
CIRCULATION (2005)
G protein-coupled receptor kinase 2-mediated phosphorylation of ezrin is required for G protein-coupled receptor-dependent reorganization of the actin cytoskeleton
SH Cant et al.
MOLECULAR BIOLOGY OF THE CELL (2005)
Transduction of receptor signals by β-arrestins
RJ Leftowitz et al.
SCIENCE (2005)
G protein-coupled receptor kinase 2 in multiple sclerosis and experimental autoimmune encephalomyelitis
A Vroon et al.
JOURNAL OF IMMUNOLOGY (2005)
Endogenous p53 protects vascular smooth muscle cells from apoptosis and reduces atherosclerosis in ApoE knockout mice
J Mercer et al.
CIRCULATION RESEARCH (2005)
A GIT1/PIX/Rac/PAK signaling module regulates spine morphogenesis and synapse formation through MLC
HY Zhang et al.
JOURNAL OF NEUROSCIENCE (2005)
Twenty years of the Alzheimer's disease amyloid hypothesis: A genetic perspective
RE Tanzi et al.
CELL (2005)
Functional antagonism of different G protein-coupled receptor kinases for β-arrestin-mediated angiotensin II receptor signaling
J Kim et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
A predicted amphipathic helix mediates plasma membrane localization of GRK5
MM Thiyagarajan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Differential functional expression of human myocardial G protein receptor kinases in left ventricular cardiac diseases
N Dzimiri et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2004)
Abnormality of G-protein-coupled receptor kinases at prodromal and early stages of Alzheimer's disease:: An association with early β-amyloid accumulation
ZM Suo et al.
JOURNAL OF NEUROSCIENCE (2004)
Calcineurin/NFAT coupling participates in pathological, but not physiological, cardiac hypertrophy
BJ Wilkins et al.
CIRCULATION RESEARCH (2004)
Phosphorylation of the platelet-derived growth factor receptor-β by G protein-coupled receptor kinase-2 reduces receptor signaling and interaction with the Na+/H+ exchanger regulatory factor
KL Hildreth et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
G protein-coupled receptor kinase 5 contains a DNA-binding nuclear localization sequence
LR Johnson et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Functional analysis of muscarinic acetylcholine receptors using knockout mice
M Matsui et al.
LIFE SCIENCES (2004)
Gonadotropin-releasing hormone (GnRH) antagonists promote proapoptotic signaling in peripheral reproductive tumor cells by activating a Gαi-coupling state of the type I GnRH receptor
S Maudsley et al.
CANCER RESEARCH (2004)
Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure
AV Chobanian et al.
HYPERTENSION (2003)
Insights into G protein structure, function, and regulation
TM Cabrera-Vera et al.
ENDOCRINE REVIEWS (2003)
The cholinergic hypothesis of age and Alzheimer's disease-related cognitive deficits: Recent challenges and their implications for novel drug development
AV Terry et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2003)
Nuclear localization of α-synuclein and its interaction with histones
J Goers et al.
BIOCHEMISTRY (2003)
The G-protein-coupled receptors in the human genome form five main families.: Phylogenetic analysis, paralogon groups, and fingerprints
R Fredriksson et al.
MOLECULAR PHARMACOLOGY (2003)
Histone deacetylases (HDACs): characterization of the classical HDAC family
AJM De Ruijter et al.
BIOCHEMICAL JOURNAL (2003)
S1P induces FA remodeling in human pulmonary endothelial cells: role of Rac, GIT1, FAK, and paxillin
Y Shikata et al.
JOURNAL OF APPLIED PHYSIOLOGY (2003)
Toll-like receptor-4 (TLR4) signaling augments chemokine-induced neutrophil migration by modulating cell surface expression of chemokine receptors
J Fan et al.
NATURE MEDICINE (2003)
The role of the novel adipocyte-derived hormone adiponectin in human disease
JJ Díez et al.
EUROPEAN JOURNAL OF ENDOCRINOLOGY (2003)
Regulation of g protein-coupled receptor kinases and arrestins during receptor desensitization
TA Kohout et al.
MOLECULAR PHARMACOLOGY (2003)
Mechanisms of regulation of the expression and function of G protein-coupled receptor kinases
P Penela et al.
CELLULAR SIGNALLING (2003)
Phosphorylation of the platelet-derived growth factor receptor-β and epidermal growth factor receptor by G protein-coupled receptor kinase-2 -: Mechanisms for selectivity of desensitization
NJ Freedman et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Neuroprotective and neurorestorative strategies for Parkinson's disease
TM Dawson et al.
NATURE NEUROSCIENCE (2002)
Medicine - The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
J Hardy et al.
SCIENCE (2002)
Identification of G protein-coupled receptor genes from the human genome sequence
S Takeda et al.
FEBS LETTERS (2002)
Interactions between opioid and chemokine receptors: heterologous desensitization
AD Steele et al.
CYTOKINE & GROWTH FACTOR REVIEWS (2002)
Akt/Protein kinase B promotes organ growth in transgenic mice
T Shioi et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
Vascular-targeted overexpression of G protein-coupled receptor kinase-2 in transgenic mice attenuates β-adrenergic receptor signaling and increases resting blood pressure
AD Eckhart et al.
MOLECULAR PHARMACOLOGY (2002)
Distribution of G-protein-coupled receptor kinase (GRK) isoforms 2, 3, 5 and 6 mRNA in the rat brain
M Erdtmann-Vourliotis et al.
MOLECULAR BRAIN RESEARCH (2001)
Deposition of Alzheimer's vascular amyloid-β is associated with decreased expression of brain L-3-hydroxyacyl-coenzyme A dehydrogenase (ERAB)
J Frackowiak et al.
BRAIN RESEARCH (2001)
Lack of mitochondrial trifunctional protein in mice causes neonatal hypoglycemia and sudden death
JA Ibdah et al.
JOURNAL OF CLINICAL INVESTIGATION (2001)
Myocardial function in hearts with transgenic overexpression of the G protein-coupled receptor kinase 5
EP Chen et al.
ANNALS OF THORACIC SURGERY (2001)
Synucleins are a novel class of substrates for G protein-coupled receptor kinases
AN Pronin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
G protein-coupled receptor kinase-5 regulates thrombin-activated signaling in endothelial cells
C Tiruppathi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
The β2-adrenergic receptor mediates extracellular signal-regulated kinase activation via assembly of a multi-receptor complex with the epidermal growth factor receptor
S Maudsley et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Five members of a novel Ca2+-binding protein (CABP) subfamily with similarity to calmodulin
F Haeseleer et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
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