相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。A technological and regulatory outlook on CRISPR crop editing
Rea Globus et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2018)
CRISPR/Cas9 in plants: at play in the genome and at work for crop improvement
Babar Hussain et al.
BRIEFINGS IN FUNCTIONAL GENOMICS (2018)
Generation and Characterization of a CYP2C11-Null Rat Model by Using the CRISPR/Cas9 Method
Yuan Wei et al.
DRUG METABOLISM AND DISPOSITION (2018)
Partial DNA-guided Cas9 enables genome editing with reduced off-target activity
Hao Yin et al.
NATURE CHEMICAL BIOLOGY (2018)
p53 inhibits CRISPR-Cas9 engineering in human pluripotent stem cells
Robert J. Ihry et al.
NATURE MEDICINE (2018)
CRISPR-Cas9 genome editing induces a p53-mediated DNA damage response
Emma Haapaniemi et al.
NATURE MEDICINE (2018)
CRISPR off-target analysis in genetically engineered rats and mice
Keith R. Anderson et al.
NATURE METHODS (2018)
High-efficiency genome editing using a dmc1 promoter-controlled CRISPR/Cas9 system in maize
Chao Feng et al.
PLANT BIOTECHNOLOGY JOURNAL (2018)
A Welcome Proposal to Amend the GMO Legislation of the EU
Dennis Eriksson et al.
TRENDS IN BIOTECHNOLOGY (2018)
Genetic variation may confound analysis of CRISPR-Cas9 off-target mutations
Guanqun Wang et al.
CELL DISCOVERY (2018)
Novel Features and Considerations for ERA and Regulation of Crops Produced by Genome Editing
Nina Duensing et al.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2018)
A large-scale whole-genome sequencing analysis reveals highly specific genome editing by both Cas9 and Cpf1 (Cas12a) nucleases in rice
Xu Tang et al.
GENOME BIOLOGY (2018)
A future scenario of the global regulatory landscape regarding genome-edited crops
Tetsuya Ishii et al.
GM CROPS & FOOD-BIOTECHNOLOGY IN AGRICULTURE AND THE FOOD CHAIN (2017)
Canadian regulatory perspectives on genome engineered crops
Stuart J. Smyth
GM CROPS & FOOD-BIOTECHNOLOGY IN AGRICULTURE AND THE FOOD CHAIN (2017)
Time for a New EU Regulatory Framework for GM Crops?
Charlotta Zetterberg et al.
JOURNAL OF AGRICULTURAL & ENVIRONMENTAL ETHICS (2017)
Gene editing in legal limbo in Europe
[Anonymous]
NATURE (2017)
Mapping the genomic landscape of CRISPR-Cas9 cleavage
Peter Cameron et al.
NATURE METHODS (2017)
CIRCLE-seq: a highly sensitive in vitro screen for genome-wide CRISPR Cas9 nuclease off-targets
Shengdar Q. Tsai et al.
NATURE METHODS (2017)
Endogenous sequence patterns predispose the repair modes of CRISPR/Cas9-induced DNA double-stranded breaks in Arabidopsis thaliana
Giang T. H. Vu et al.
PLANT JOURNAL (2017)
CRISPR-Cas9 Targeted Mutagenesis Leads to Simultaneous Modification of Different Homoeologous Gene Copies in Polyploid Oilseed Rape (Brassica napus)
Janina Braatz et al.
PLANT PHYSIOLOGY (2017)
Fostering responsible research with genome editing technologies: a European perspective
Herve Chneiweiss et al.
TRANSGENIC RESEARCH (2017)
New GMO regulations for old: Determining a new future for EU crop biotechnology
John Davison et al.
GM CROPS & FOOD-BIOTECHNOLOGY IN AGRICULTURE AND THE FOOD CHAIN (2017)
Rapid generation of a transgene-free powdery mildew resistant tomato by genome deletion
Vladimir Nekrasov et al.
SCIENTIFIC REPORTS (2017)
Detection of on-target and off-target mutations generated by CRISPR/Cas9 and other sequence-specific nucleases
Julia Zischewski et al.
BIOTECHNOLOGY ADVANCES (2017)
Use of CRISPR systems in plant genome editing: toward new opportunities in agriculture
Agnes Ricroch et al.
EMERGING TOPICS IN LIFE SCIENCES (2017)
Scientific Opinion of the PPR Panelon the follow-up of the findings of the External Scientific Report Literature review of epidemiological studies linking exposure to pesticides and health effects'
Colin Ockleford et al.
EFSA JOURNAL (2017)
The social licence to operate: a critical review
Kieren Moffat et al.
FORESTRY (2016)
The Regulatory Status of Genome-edited Crops
Jeffrey D. Wolt et al.
PLANT BIOTECHNOLOGY JOURNAL (2016)
Keeping CRISPR/Cas on-Target
CURRENT ISSUES IN MOLECULAR BIOLOGY (2016)
High Throughput Sequencing: An Overview of Sequencing Chemistry
Sheetal Ambardar et al.
INDIAN JOURNAL OF MICROBIOLOGY (2016)
Methods for Optimizing CRISPR-Cas9 Genome Editing Specificity
Josh Tycko et al.
MOLECULAR CELL (2016)
Detecting DNA double-stranded breaks in mammalian genomes by linear amplification-mediated high-throughput genome-wide translocation sequencing
Jiazhi Hu et al.
NATURE PROTOCOLS (2016)
Regulatory hurdles for genome editing: process- vs. product-based approaches in different regulatory contexts
Thorben Sprink et al.
PLANT CELL REPORTS (2016)
Essential Features of Responsible Governance of Agricultural Biotechnology
Sarah Hartley et al.
PLOS BIOLOGY (2016)
An integrated multi-omics analysis of the NK603 Roundup-tolerant GM maize reveals metabolism disturbances caused by the transformation process
Robin Mesnage et al.
SCIENTIFIC REPORTS (2016)
Towards an alignment of activities, aspirations and stakeholders for responsible innovation
Rider W. Foley et al.
JOURNAL OF RESPONSIBLE INNOVATION (2016)
Broadening the lens for the governance of emerging technologies: Care ethics and agricultural biotechnology
Christopher J. Preston et al.
TECHNOLOGY IN SOCIETY (2016)
Guidance to develop specific protection goals options for environmental risk assessment at EFSA, in relation to biodiversity and ecosystem services
Diane Benford et al.
EFSA JOURNAL (2016)
Digenome-seq: genome-wide profiling of CRISPR-Cas9 off-target effects in human cells
Daesik Kim et al.
NATURE METHODS (2015)
A prudent path forward for genomic engineering and germline gene modification
David Baltimore et al.
SCIENCE (2015)
Biotechnological uses of RNAi in plants: risk assessment considerations
Josep M. Casacuberta et al.
TRENDS IN BIOTECHNOLOGY (2015)
Regulatory uncertainty over genome editing
Huw D. Jones
NATURE PLANTS (2015)
Regulatory framework for gene editing and other new breeding techniques (NBTs) in Argentina
Agustina I. Whelan et al.
GM CROPS & FOOD-BIOTECHNOLOGY IN AGRICULTURE AND THE FOOD CHAIN (2015)
GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases
Shengdar Q. Tsai et al.
NATURE BIOTECHNOLOGY (2015)
Analysis of off-target effects of CRISPR/Cas-derived RNA-guided endonucleases and nickases
Seung Woo Cho et al.
GENOME RESEARCH (2014)
Improving CRISPR-Cas nuclease specificity using truncated guide RNAs
Yanfang Fu et al.
NATURE BIOTECHNOLOGY (2014)
RNAi-based GM plants: food for thought for risk assessors
Matthew Ramon et al.
PLANT BIOTECHNOLOGY JOURNAL (2014)
The CRISPR/Cas9 system produces specific and homozygous targeted gene editing in rice in one generation
Hui Zhang et al.
PLANT BIOTECHNOLOGY JOURNAL (2014)
Precise plant breeding using new genome editing techniques: opportunities, safety and regulation in the EU
Frank Hartung et al.
PLANT JOURNAL (2014)
Multigeneration analysis reveals the inheritance, specificity, and patterns of CRISPR/Cas-induced gene modifications in Arabidopsis
Zhengyan Feng et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Modern methodologies and tools for human hazard assessment of chemicals
EFSA JOURNAL (2014)
Plant variety and cultivar identification: advances and prospects
Nicholas Kibet Korir et al.
CRITICAL REVIEWS IN BIOTECHNOLOGY (2013)
Nucleotide-resolution DNA double-strand break mapping by next-generation sequencing
Nicola Crosetto et al.
NATURE METHODS (2013)
Developing a framework for responsible innovation
Jack Stilgoe et al.
RESEARCH POLICY (2013)
Dying Bees and the Social Production of Ignorance
Daniel Lee Kleinman et al.
SCIENCE TECHNOLOGY & HUMAN VALUES (2013)
Ethics of Science for Policy in the Environmental Governance of Biotechnology: MON810 Maize in Europe
Fern Wickson et al.
ETHICS POLICY & ENVIRONMENT (2012)
Molecular profiling - a tool for addressing emerging gaps in the comparative risk assessment of GMOs
Jack A. Heinemann et al.
ENVIRONMENT INTERNATIONAL (2011)
Environmental risk assessment of genetically modified plants - concepts and controversies
Angelika Hilbeck et al.
Environmental Sciences Europe (2011)
Guidance for risk assessment of food and feed from genetically modified plants EFSA Panel on Genetically Modified Organisms (GMO)
Hans Christer Andersson et al.
EFSA JOURNAL (2011)
Guidance on the risk assessment of the application of nanoscience and nanotechnologies in the food and feed chain EFSA Scientific Committee
Boris Antunovic et al.
EFSA JOURNAL (2011)
Guidance on the environmental risk assessment of genetically modified plants
Hans Christer Andersson et al.
EFSA JOURNAL (2010)
Characterisation of 3′ transgene insertion site and derived mRNAs in MON810 YieldGard® maize
Alessio Rosati et al.
PLANT MOLECULAR BIOLOGY (2008)
Rectangular and hexagonal grids used for observation, experiment and simulation in ecology
Colin P. D. Birch et al.
ECOLOGICAL MODELLING (2007)
Transgenic crops expressing Bacillus thuringiensis toxins and biological control
J Romeis et al.
NATURE BIOTECHNOLOGY (2006)
Science in society: re-evaluating the deficit model of public attitudes
P Sturgis et al.
PUBLIC UNDERSTANDING OF SCIENCE (2004)
Characterisation of the Roundup Ready soybean insert
P Windels et al.
EUROPEAN FOOD RESEARCH AND TECHNOLOGY (2001)
Plant allergens and pathogenesis-related proteins - What do they have in common?
K Hoffmann-Sommergruber
INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY (2000)