期刊
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
卷 6, 期 12, 页码 16976-+出版社
AMER CHEMICAL SOC
DOI: 10.1021/acssuschemeng.8b04339
关键词
In water; Sulfonyl chlorides; Sulfonylation; Sulfonylated N-heteroaromatics; Metal-free
资金
- Hunan University of Science and Engineering
- National Natural Science Foundation of China [21302048]
An ecofriendly and practical method for the efficient synthesis of various sulfonylated N-heteroaromatics in water under metal-free, organic-solvent-free, neutral, and mild reaction conditions was developed. The employment of readily available reagents, wide substrate scope, high chemoselectivity, and regioselectivity make this protocol very practical. Importantly, the pure products can be easily obtained via filtration and washing by alcohol without extraction and recrystallization.
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