期刊
POLYMERS
卷 10, 期 12, 页码 -出版社
MDPI
DOI: 10.3390/polym10121323
关键词
poly (acrylic acid); bacterial cellulose; hydrogel; wound dressing; antimicrobial
资金
- CSE start-up grant, Flinders University
- International Research Grant (International Laboratory for Health Technologies), South Australia
- Training Project of Innovation Team of Colleges and Universities in Tianjin, China [TD13-5043]
This investigation examines the combination of poly (acrylic acid) (PAA) and bacterial cellulose (BC) nanofibers to synthesize hydrogel hybrid composites used for wound dressing application. Amoxicillin (AM) was also grafted onto the composites for drug release. Fourier transform infrared analysis and scanning electron microscopy conducted revealed the structure and porosity of the composite being developed, as well as the successful fabrication of BC-PAA composites. The results of mechanical testing and hygroscopicity revealed that the composite shows higher stability than hydrogels which are currently used worldwide, albeit with a slight reduction in swelling capabilities. However, the composite was revealed to be responsive to a rise in pH values with an increase in composite swelling and drug release. These results together with their morphological characteristics suggest that BC-PAA hydrogel hybrid composite is a promising candidate for wound dressing application.
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