相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Staining of HLA-DR, Ibal and CD68 in human microglia reveals partially overlapping expression depending on cellular morphology and pathology
Debbie A. E. Hendrickx et al.
JOURNAL OF NEUROIMMUNOLOGY (2017)
LRRK2 levels in immune cells are increased in Parkinson'sdisease
D. A. Cook et al.
NPJ PARKINSONS DISEASE (2017)
Presynaptic dopaminergic terminal imaging and non-motor symptoms assessment of Parkinson's disease: evidence for dopaminergic basis?
M. A. Qamar et al.
NPJ PARKINSONS DISEASE (2017)
LRRK2 BAC transgenic rats develop progressive, L-DOPA-responsive motor impairment, and deficits in dopamine circuit function
Max Sloan et al.
HUMAN MOLECULAR GENETICS (2016)
[11C]PBR28 PET imaging is sensitive to neuroinflammation in the aged rat
Matthew D. Walker et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2015)
Systemic inflammation and microglial activation: systematic review of animal experiments
Inge C. M. Hoogland et al.
JOURNAL OF NEUROINFLAMMATION (2015)
Behavioral, neurochemical, and pathologic alterations in bacterial artificial chromosome transgenic G2019S leucine-rich repeated kinase 2 rats
Jang-Won Lee et al.
NEUROBIOLOGY OF AGING (2015)
Imaging robust microglial activation after lipopolysaccharide administration in humans with PET
Christine M. Sandiego et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
LRRK2 pathobiology in Parkinson's disease
Ian Martin et al.
JOURNAL OF NEUROCHEMISTRY (2014)
LRRK2 and neuroinflammation: partners in crime in Parkinson's disease?
Isabella Russo et al.
JOURNAL OF NEUROINFLAMMATION (2014)
The Prevalence of Parkinson's Disease: A Systematic Review and Meta-analysis
Tamara Pringsheim et al.
MOVEMENT DISORDERS (2014)
Genetic and pharmacological evidence that G2019S LRRK2 confers a hyperkinetic phenotype, resistant to motor decline associated with aging
Francesco Longo et al.
NEUROBIOLOGY OF DISEASE (2014)
Further characterisation of the LPS model of Parkinson's disease: A comparison of intra-nigral and intra-striatal lipopolysaccharide administration on motor function, microgliosis and nigrostriatal neurodegeneration in the rat
Deirdre B. Hoban et al.
BRAIN BEHAVIOR AND IMMUNITY (2013)
The role of inflammation in sporadic and familial Parkinson's disease
Michela Deleidi et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2013)
Multiple Intranigral Unilateral LPS Infusion Protocol Generates a Persistent Cognitive Impairment without Cumulative Dopaminergic Impairment
Ana Marcia Delattre et al.
CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS (2013)
In-vivo measurement of LDOPA uptake, dopamine reserve and turnover in the rat brain using [F-18]FDOPA PET
Matthew D. Walker et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2013)
Microglia, Amyloid, and Glucose Metabolism in Parkinson's Disease with and without Dementia
Paul Edison et al.
NEUROPSYCHOPHARMACOLOGY (2013)
Diffusion-weighted imaging and its relationship to microglial activation in parkinsonian syndromes
Christopher Kobylecki et al.
PARKINSONISM & RELATED DISORDERS (2013)
(G2019S) LRRK2 activates MKK4-JNK pathway and causes degeneration of SN dopaminergic neurons in a transgenic mouse model of PD
C-Y Chen et al.
CELL DEATH AND DIFFERENTIATION (2012)
LRRK2 functions as a Wnt signaling scaffold, bridging cytosolic proteins and membrane-localized LRP6
Daniel C. Berwick et al.
HUMAN MOLECULAR GENETICS (2012)
Microglial activation in healthy aging
Alie Schuitemaker et al.
NEUROBIOLOGY OF AGING (2012)
Endotoxin-induced systemic inflammation activates microglia: [11C]PBR28 positron emission tomography in nonhuman primates
Jonas Hannestad et al.
NEUROIMAGE (2012)
Neuroinflammation and α-Synuclein Dysfunction Potentiate Each Other, Driving Chronic Progression of Neurodegeneration in a Mouse Model of Parkinson's Disease
Hui-Ming Gao et al.
ENVIRONMENTAL HEALTH PERSPECTIVES (2011)
Parkinson's disease-linked LRRK2 is expressed in circulating and tissue immune cells and upregulated following recognition of microbial structures
Mansoureh Hakimi et al.
JOURNAL OF NEURAL TRANSMISSION (2011)
Dopaminergic Neuronal Loss, Reduced Neurite Complexity and Autophagic Abnormalities in Transgenic Mice Expressing G2019S Mutant LRRK2
David Ramonet et al.
PLOS ONE (2011)
Use of [F-18]FDOPA-PET for in vivo evaluation of dopaminergic dysfunction in unilaterally 6-OHDA-lesioned rats
Kiyoshi Kyono et al.
EJNMMI RESEARCH (2011)
Enhanced Striatal Dopamine Transmission and Motor Performance with LRRK2 Overexpression in Mice Is Eliminated by Familial Parkinson's Disease Mutation G2019S
Xianting Li et al.
JOURNAL OF NEUROSCIENCE (2010)
Dopamine Turnover Increases in Asymptomatic LRRK2 Mutations Carriers
Vesna Sossi et al.
MOVEMENT DISORDERS (2010)
Impaired dopaminergic neurotransmission and microtubule-associated protein tau alterations in human LRRK2 transgenic mice
H. L. Melrose et al.
NEUROBIOLOGY OF DISEASE (2010)
[C-11]-PK11195 PET: Quantification of neuroinflammation and a monitor of anti-inflammatory treatment in Parkinson's disease?
A. L. Bartels et al.
PARKINSONISM & RELATED DISORDERS (2010)
Positron Emission Tomography Kinetic Modeling Algorithms for Small Animal Dopaminergic System Imaging
Geoffrey J. Topping et al.
SYNAPSE (2010)
Systemic Inflammation Induces Acute Behavioral and Cognitive Changes and Accelerates Neurodegenerative Disease
Colm Cunningham et al.
BIOLOGICAL PSYCHIATRY (2009)
Phenotype, genotype, and worldwide genetic penetrance of LRRK2-associated Parkinson's disease: a case-control study
Daniel G. Healy et al.
LANCET NEUROLOGY (2008)
Lrrk2 and chronic inflammation are linked to pallido-ponto-nigral degeneration caused by the N279K tau mutation
Judith Miklossy et al.
ACTA NEUROPATHOLOGICA (2007)
Performance measurement of the microPET focus 120 scanner
Jin Su Kim et al.
JOURNAL OF NUCLEAR MEDICINE (2007)
In vivo measurement of density and affinity of the monoamine vesicular transporter in a unilateral 6-hydroxydopamine rat model of PD
Vesna Sossi et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2007)
Human retinal pigment epithelial cell implants ameliorate motor deficits in two rat models of Parkinson disease
Ivan L. Cepeda et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2007)
Systemic LPS causes chronic neuroinflammation and progressive neurodegeneration
Liya Qin et al.
GLIA (2007)
In vivo imaging of microglial activation with [11C](R)-PK11195 PET in idiopathic Parkinson's disease
A Gerhard et al.
NEUROBIOLOGY OF DISEASE (2006)
Exaggerated neuroinflammation and sickness behavior in aged mice after activation of the peripheral innate immune system
JP Godbout et al.
FASEB JOURNAL (2005)
Microglial activation and dopamine terminal loss in early Parkinson's disease
Y Ouchi et al.
ANNALS OF NEUROLOGY (2005)
Development and evaluation of an automated atlas-based image analysis method for microPET studies of the rat brain
DJ Rubins et al.
NEUROIMAGE (2003)
Peripheral infection evokes exaggerated sickness behaviour in pre-clinical murine prion disease
MI Combrinck et al.
NEUROSCIENCE (2002)
A reversible tracer analysis approach to the study of effective dopamine turnover
V Sossi et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2001)
The single intranigral injection of LPS as a new model for studying the selective effects of inflammatory reactions on dopaminergic system
AJ Herrera et al.
NEUROBIOLOGY OF DISEASE (2000)
分享论文
