4.7 Review

Eukaryotic elongation factor 2 kinase as a drug target in cancer, and in cardiovascular and neurodegenerative diseases

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Cardiac & Cardiovascular Systems

Eukaryotic elongation factor 2 kinase mediates monocrotaline-induced pulmonary arterial hypertension via reactive oxygen species-dependent vascular remodeling

Satoshi Kameshima et al.

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2015)

Article Biochemistry & Molecular Biology

Regulated stability of eukaryotic elongation factor 2 kinase requires intrinsic but not ongoing activity

Xuemin Wang et al.

BIOCHEMICAL JOURNAL (2015)

Article Biochemistry & Molecular Biology

Elongation Factor 2 Kinase Is Regulated by Proline Hydroxylation and Protects Cells during Hypoxia

Claire E. J. Moore et al.

MOLECULAR AND CELLULAR BIOLOGY (2015)

Article Multidisciplinary Sciences

mTORC1-mediated translational elongation limits intestinal tumour initiation and growth

William J. Faller et al.

NATURE (2015)

Review Nutrition & Dietetics

AMP-Activated Protein Kinase: Maintaining Energy Homeostasis at the Cellular and Whole-Body Levels

D. Grahame Hardie

ANNUAL REVIEW OF NUTRITION, VOL 34 (2014)

Article Biochemistry & Molecular Biology

How does oncogene transformation render tumor cells hypersensitive to nutrient deprivation?

Gabriel Leprivier et al.

BIOESSAYS (2014)

Article Biochemistry & Molecular Biology

Synthesis and biological evaluation of pyrido[2,3-d]pyrimidine-2,4-dione derivatives as eEF-2K inhibitors

Ramakrishna Edupuganti et al.

BIOORGANIC & MEDICINAL CHEMISTRY (2014)

Article Cardiac & Cardiovascular Systems

Impairing Eukaryotic Elongation Factor 2 Kinase Activity Decreases Atherosclerotic Plaque Formation

Peng Zhang et al.

CANADIAN JOURNAL OF CARDIOLOGY (2014)

Article Biochemistry & Molecular Biology

The Molecular Mechanism of Eukaryotic Elongation Factor 2 Kinase Activation

Clint D. J. Tavares et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2014)

Article Biochemistry & Molecular Biology

A Conserved Loop in the Catalytic Domain of Eukaryotic Elongation Factor 2 Kinase Plays a Key Role in Its Substrate Specificity

Claire E. Moore et al.

MOLECULAR AND CELLULAR BIOLOGY (2014)

Article Biochemistry & Molecular Biology

Eukaryotic Elongation Factor 2 Kinase Activity Is Controlled by Multiple Inputs from Oncogenic Signaling

Xuemin Wang et al.

MOLECULAR AND CELLULAR BIOLOGY (2014)

Review Cell Biology

mTORC1 signaling controls multiple steps in ribosome biogenesis

Valentina Iadevaia et al.

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2014)

Review Neurosciences

Elongation factor-2 phosphorylation in dendrites and the regulation of dendritic mRNA translation in neurons

Christopher Heise et al.

FRONTIERS IN CELLULAR NEUROSCIENCE (2014)

Article Biochemical Research Methods

High-Throughput Screens for eEF-2 Kinase

Ashwini K. Devkota et al.

JOURNAL OF BIOMOLECULAR SCREENING (2014)

Article Cardiac & Cardiovascular Systems

Eukaryotic elongation factor 2 kinase regulates the development of hypertension through oxidative stress-dependent vascular inflammation

Tatsuya Usui et al.

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2013)

Article Biochemistry & Molecular Biology

The eEF2 Kinase Confers Resistance to Nutrient Deprivation by Blocking Translation Elongation

Gabriel Leprivier et al.

Article Biochemistry & Molecular Biology

Identification of autophosphorylation sites in eukaryotic elongation factor-2 kinase

Sebastien Pyr Dit Ruys et al.

BIOCHEMICAL JOURNAL (2012)

Article Biochemistry & Molecular Biology

Coupled Activation and Degradation of eEF2K Regulates Protein Synthesis in Response to Genotoxic Stress

Flore Kruiswijk et al.

SCIENCE SIGNALING (2012)

Article Biochemistry & Molecular Biology

Exploring calmodulin-related proteins, which mediate development of hypertension, in vascular tissues of spontaneous hypertensive rats

Tatsuya Usui et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2011)

Article Multidisciplinary Sciences

NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses

Anita E. Autry et al.

NATURE (2011)

Article Multidisciplinary Sciences

Global quantification of mammalian gene expression control

Bjoern Schwanhaeusser et al.

NATURE (2011)

Article Chemistry, Medicinal

Inhibition of eEF2-K by thieno[2,3-b]pyridine analogues

Jeffrey W. Lockman et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2010)

Review Biochemistry & Molecular Biology

The alpha-kinase family: an exceptional branch on the protein kinase tree

Jeroen Middelbeek et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2010)

Article Biochemistry & Molecular Biology

Crystal Structure of the α-Kinase Domain of Dictyostelium Myosin Heavy Chain Kinase A

Qilu Ye et al.

SCIENCE SIGNALING (2010)

Article Hematology

Oxidized LDL-Mediated Macrophage Survival Involves Elongation Factor-2 Kinase

Johnny H. Chen et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2009)

Review Cell Biology

Making synaptic plasticity and memory last: mechanisms of translational regulation

Joel D. Richter et al.

GENES & DEVELOPMENT (2009)

Review Neurosciences

Translational Control of Long-Lasting Synaptic Plasticity and Memory

Mauro Costa-Mattioli et al.

NEURON (2009)

Review Biochemistry & Molecular Biology

Signalling to translation: how signal transduction pathways control the protein synthetic machinery

Christopher G. Proud

BIOCHEMICAL JOURNAL (2007)

Review Biochemistry & Molecular Biology

Alpha-kinases: analysis of the family and comparison with conventional protein kinases

D Drennan et al.

PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY (2004)

Article Biochemistry & Molecular Biology

Regulation of elongation factor-2 kinase by pH

MV Dorovkov et al.

BIOCHEMISTRY (2002)

Article Biochemistry & Molecular Biology

Regulation of elongation factor 2 kinase by p90RSK1 and p70 S6 kinase

XM Wang et al.

EMBO JOURNAL (2001)

Article Biochemistry & Molecular Biology

Specificity and mechanism of action of some commonly used protein kinase inhibitors

SP Davies et al.

BIOCHEMICAL JOURNAL (2000)

Article Biochemistry & Molecular Biology

Novel compounds, '1,3-selenazine derivatives' as specific inhibitors of eukaryotic elongation factor-2 kinase

SI Cho et al.

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2000)