期刊
CURRENT STEM CELL RESEARCH & THERAPY
卷 14, 期 5, 页码 428-436出版社
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/1574888X13666181002151330
关键词
Cancer stem cells; tumor microenvironment; integrin alpha 6; laminins; self-renewal; cell signalling
资金
- NIH [R15CA182889-01]
- Center of Biomedical Research at Oakland University
Cancer is a highly prevalent and potentially terminal disease that affects millions of individuals worldwide. Here, we review the literature exploring the intricacies of stem cells bearing tumorigenic characteristics and collect evidence demonstrating the importance of integrin alpha 6 (ITGA6, also blown as CD49f) in Cancer Stem Cell (CSC) activity. ITGA6 is commonly used to identify CSC populations in various tissues and plays an important role sustaining the self-renewal of CSCs by interconnecting them with the tumorigenic microenvironment.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据