期刊
MATERIALS
卷 12, 期 1, 页码 -出版社
MDPI
DOI: 10.3390/ma12010186
关键词
pulsed laser ablation in water; pulsed laser ablation in air; ZnO nanoparticles; biomedical materials; PLLA-scaffold; antibacterial properties
类别
资金
- Tomsk State University competitiveness improvement program
- Japan Society for the Promotion of Science (JSPS) [16K04904]
- scholarship program of the President of the Russian Federation
- Grants-in-Aid for Scientific Research [16K04904] Funding Source: KAKEN
Here, we report on ZnO nanoparticles (NPs) generated by nanosecond pulsed laser (Nd:YAG, 1064 nm) through ablation of metallic Zn target in water and air and their comparative analysis as potential nanomaterials for biomedical applications. The prepared nanomaterials were carefully characterized in terms of their structure, composition, morphology and defects. It was found that in addition to the main wurtzite ZnO phase, which is conventionally prepared and reported by others, the sample laser generated in air also contained some amount of monoclinic zinc hydroxynitrate. Both nanomaterials were then used to modify model wound dressings based on biodegradable poly L-lactic acid. The as-prepared model dressings were tested as biomedical materials with bactericidal properties towards S. aureus and E. coli strains. The advantages of the NPs prepared in air over their counterparts generated in water found in this work are discussed.
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