期刊
HOLISTIC NURSING PRACTICE
卷 33, 期 5, 页码 259-265出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/HNP.0000000000000311
关键词
intestinal microbiota; obesity; obesity-related diseases; traditional Chinese medicine
资金
- Natural Science Foundation of Guangdong in China [2016A030313824]
- Traditional Chinese Medicine Bureau of Guangdong in China [20161065]
- National Health and Family Planning Commission of Guangdong in China [A2016583, A2017228, A2017140]
- Student Innovation and Entrepreneurship Training Program of Jinan University in China [CX17042, 201810559144]
The incidence of obesity and obesity-related diseases, such as type 2 diabetes mellitus and nonalcoholic fatty liver disease, is increasing worldwide, which threatens quality of life and human health. The toxins in the stool enter the body and blood and then cause a variety of diseases; this quote illustrates that the Chinese ancients recognized the negative effects of harmful intestinal metabolites on the body. As the largest microecosystem in the human body, intestinal microbiota and their metabolites affect the nutrition, metabolism, and immune function of the host, which is an important pathogenic factor in obesity and obesity-related diseases. Herbal-based supplements are used for many years in the treatment of obesity, type 2 diabetes mellitus, and nonalcoholic fatty liver disease in China. Traditional herbal medicine contains fiber, polyphenols, and polysaccharides that exert prebiotics-like activities in the prevention and treatment of obesity-related diseases. This article provides a systematic mini-review of the literature concerning traditional Chinese medicine for modulation of the intestinal microbiota to ameliorate obesity, type 2 diabetes mellitus, and nonalcoholic fatty liver disease in China. Initially, the relationship between traditional Chinese medicine and intestinal microbiota was introduced, followed by specific research results on this relationship based on 25 original articles. Therefore, this mini-review will provide a complementary and integrative approach for the treatment of these obesity-related diseases.
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