相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Aging and neurodegeneration are associated with increased mutations in single human neurons
Michael A. Lodato et al.
SCIENCE (2018)
Different mutational rates and mechanisms in human cells at pregastrulation and neurogenesis
Taejeong Bae et al.
SCIENCE (2018)
Neuroinflammation and Peripheral Immune Infiltration in Parkinson's Disease: An Autoimmune Hypothesis
Angela J. Monahan et al.
CELL TRANSPLANTATION (2018)
Genetic compendium of 1511 human brains available through the UK Medical Research Council Brain Banks Network Resource
Michael J. Keogh et al.
GENOME RESEARCH (2017)
The role of peripheral immune cells in the CNS in steady state and disease
Marco Prinz et al.
NATURE NEUROSCIENCE (2017)
Clonal hematopoiesis associated with TET2 deficiency accelerates atherosclerosis development in mice
Jose J. Fuster et al.
SCIENCE (2017)
The nature of mutations induced by replication-transcription collisions
T. Sabari Sankar et al.
NATURE (2016)
The road to restoring neural circuits for the treatment of Alzheimer's disease
Rebecca G. Canter et al.
NATURE (2016)
Analysis of protein-coding genetic variation in 60,706 humans
Monkol Lek et al.
NATURE (2016)
The Evolution of Genetics: Alzheimer's and Parkinson's Diseases
Andrew Singleton et al.
NEURON (2016)
The ErbB2ΔEx16 splice variant is a major oncogenic driver in breast cancer that promotes a pro-metastatic tumor microenvironment
J. Turpin et al.
ONCOGENE (2016)
Exome sequencing in dementia with Lewy bodies
M. J. Keogh et al.
TRANSLATIONAL PSYCHIATRY (2016)
SnapShot: Genetics of ALS and FTD
Rita Guerreiro et al.
CELL (2015)
Loss of TET2 in hematopoietic cells leads to DNA hypermethylation of active enhancers and induction of leukemogenesis
Kasper D. Rasmussen et al.
GENES & DEVELOPMENT (2015)
Effect of Mutation Order on Myeloproliferative Neoplasms
Christina A. Ortmann et al.
NEW ENGLAND JOURNAL OF MEDICINE (2015)
Somatic mutation in single human neurons tracks developmental and transcriptional history
Michael A. Lodato et al.
SCIENCE (2015)
Leukemia-Associated Somatic Mutations Drive Distinct Patterns of Age-Related Clonal Hemopoiesis
Thomas McKerrell et al.
CELL REPORTS (2015)
DNMT3A in haematological malignancies
Liubin Yang et al.
NATURE REVIEWS CANCER (2015)
Pyroglutamylated amyloid-β is associated with hyperphosphorylated tau and severity of Alzheimer's disease
Markus Mandler et al.
ACTA NEUROPATHOLOGICA (2014)
Subclonal variant calling with multiple samples and prior knowledge
Moritz Gerstung et al.
BIOINFORMATICS (2014)
The Human Gene Mutation Database: building a comprehensive mutation repository for clinical and molecular genetics, diagnostic testing and personalized genomic medicine
Peter D. Stenson et al.
HUMAN GENETICS (2014)
Clonal Hematopoiesis and Blood-Cancer Risk Inferred from Blood DNA Sequence
Giulio Genovese et al.
NEW ENGLAND JOURNAL OF MEDICINE (2014)
Age-Related Clonal Hematopoiesis Associated with Adverse Outcomes
Siddhartha Jaiswal et al.
NEW ENGLAND JOURNAL OF MEDICINE (2014)
Distinctive patterns of DNA methylation associated with Parkinson disease Identification of concordant epigenetic changes in brain and peripheral blood leukocytes
Eliezer Masliah et al.
EPIGENETICS (2013)
Signatures of mutational processes in human cancer
Ludmil B. Alexandrov et al.
NATURE (2013)
Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples
Kristian Cibulskis et al.
NATURE BIOTECHNOLOGY (2013)
Monetary Costs of Dementia in the United States
NEW ENGLAND JOURNAL OF MEDICINE (2013)
Half or more of the somatic mutations in cancers of self-renewing tissues originate prior to tumor initiation
Cristian Tomasetti et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
VarScan 2: Somatic mutation and copy number alteration discovery in cancer by exome sequencing
Daniel C. Koboldt et al.
GENOME RESEARCH (2012)
An integrated map of genetic variation from 1,092 human genomes
David M. Altshuler et al.
NATURE (2012)
Recurrent somatic TET2 mutations in normal elderly individuals with clonal hematopoiesis
Lambert Busque et al.
NATURE GENETICS (2012)
Evolution of the cancer genome
Lucy R. Yates et al.
NATURE REVIEWS GENETICS (2012)
Reliable detection of subclonal single-nucleotide variants in tumour cell populations
Moritz Gerstung et al.
NATURE COMMUNICATIONS (2012)
Integrative genomics viewer
James T. Robinson et al.
NATURE BIOTECHNOLOGY (2011)
A framework for variation discovery and genotyping using next-generation DNA sequencing data
Mark A. DePristo et al.
NATURE GENETICS (2011)
The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data
Aaron McKenna et al.
GENOME RESEARCH (2010)
Prion-like transmission of protein aggregates in neurodegenerative diseases
Patrik Brundin et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)
ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data
Kai Wang et al.
NUCLEIC ACIDS RESEARCH (2010)
Analysis of Genetic Inheritance in a Family Quartet by Whole-Genome Sequencing
Jared C. Roach et al.
SCIENCE (2010)
VarScan: variant detection in massively parallel sequencing of individual and pooled samples
Daniel C. Koboldt et al.
BIOINFORMATICS (2009)
Conformational Diversity of Wild-type Tau Fibrils Specified by Templated Conformation Change
Bess Frost et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Equal Numbers of Neuronal and Nonneuronal Cells Make the Human Brain an Isometrically Scaled-Up Primate Brain
Frederico A. C. Azevedo et al.
JOURNAL OF COMPARATIVE NEUROLOGY (2009)
PLINK: A tool set for whole-genome association and population-based linkage analyses
Shaun Purcell et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2007)
Immortal strands? Give me a break
Peter M. Lansdorp
CELL (2007)
Blood-brain barrier pathology in Alzheimer's and Parkinson's disease: Implications for drug therapy
Brinda S. Desai et al.
CELL TRANSPLANTATION (2007)
A century of Alzheimer's disease
Michel Goedert et al.
SCIENCE (2006)
Alpha-synuclein and neurodegenerative diseases
M Goedert
NATURE REVIEWS NEUROSCIENCE (2001)
Shattuck lecture - Neurodegenerative diseases and prions.
SB Prusiner
NEW ENGLAND JOURNAL OF MEDICINE (2001)
Mechanisms of programmed cell death in the developing brain
CY Kuan et al.
TRENDS IN NEUROSCIENCES (2000)
分享论文
