相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Palimpsest: an R package for studying mutational and structural variant signatures along clonal evolution in cancer
Jayendra Shinde et al.
BIOINFORMATICS (2018)
Oncogenic Signaling Pathways in The Cancer Genome Atlas
Francisco Sanchez-Vega et al.
CELL (2018)
Targeting the replication stress response in cancer
Josep V. Forment et al.
PHARMACOLOGY & THERAPEUTICS (2018)
Break-Induced Replication: The Where, The Why, and The How
J. Kramara et al.
TRENDS IN GENETICS (2018)
Driver Fusions and Their Implications in the Development and Treatment of Human Cancers
Qingsong Gao et al.
CELL REPORTS (2018)
Intragenic origins due to short G1 phases underlie oncogene-induced DNA replication stress
Morgane Macheret et al.
NATURE (2018)
Regorafenib for patients with hepatocellular carcinoma who progressed on sorafenib treatment (RESORCE): a randomised, double-blind, placebo-controlled, phase 3 trial
Jordi Bruix et al.
LANCET (2017)
A somatic-mutational process recurrently duplicates germline susceptibility loci and tissue-specific super-enhancers in breast cancers
Dominik Glodzik et al.
NATURE GENETICS (2017)
PARP inhibitors: Synthetic lethality in the clinic
Christopher J. Lord et al.
SCIENCE (2017)
Mutational signatures reveal the dynamic interplay of risk factors and cellular processes during liver tumorigenesis
Eric Letouze et al.
NATURE COMMUNICATIONS (2017)
Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma
Adrian Ally et al.
CELL (2017)
Manta: rapid detection of structural variants and indels for germline and cancer sequencing applications
Xiaoyu Chen et al.
BIOINFORMATICS (2016)
Landscape of somatic mutations in 560 breast cancer whole-genome sequences
Serena Nik-Zainal et al.
NATURE (2016)
Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer
Akihiro Fujimoto et al.
NATURE GENETICS (2016)
The tandem duplicator phenotype as a distinct genomic configuration in cancer
Francesca Menghi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Hepatocellular carcinoma
Josep M. Llovet et al.
NATURE REVIEWS DISEASE PRIMERS (2016)
Genetic Landscape and Biomarkers of Hepatocellular Carcinoma
Jessica Zucman-Rossi et al.
GASTROENTEROLOGY (2015)
Targeting the DNA Damage Response in Cancer
Mark J. O'Connor
MOLECULAR CELL (2015)
Integrative analysis of 111 reference human epigenomes
Anshul Kundaje et al.
NATURE (2015)
Whole-genome characterization of chemoresistant ovarian cancer
Ann-Marie Patch et al.
NATURE (2015)
Recurrent AAV2-related insertional mutagenesis in human hepatocellular carcinomas
Jean-Charles Nault et al.
NATURE GENETICS (2015)
Exome sequencing of hepatocellular carcinomas identifies new mutational signatures and potential therapeutic targets
Kornelius Schulze et al.
NATURE GENETICS (2015)
limma powers differential expression analyses for RNA-sequencing and microarray studies
Matthew E. Ritchie et al.
NUCLEIC ACIDS RESEARCH (2015)
HTSeq-a Python framework to work with high-throughput sequencing data
Simon Anders et al.
BIOINFORMATICS (2015)
EASL–EORTC Clinical Practice Guidelines: Management of hepatocellular carcinoma
et al.
JOURNAL OF HEPATOLOGY (2015)
ElemeNT: a computational tool for detecting core promoter elements
Anna Sloutskin et al.
TRANSCRIPTION-AUSTIN (2015)
Hepatocellular Carcinoma: Reasons for Phase III Failure and Novel Perspectives on Trial Design
Josep M. Llovet et al.
CLINICAL CANCER RESEARCH (2014)
Genomic Portrait of Resectable Hepatocellular Carcinomas: Implications of RB1 and FGF19 Aberrations for Patient Stratification
Sung-Min Ahn et al.
HEPATOLOGY (2014)
Telomerase Reverse Transcriptase Promoter Mutation Is an Early Somatic Genetic Alteration in the Transformation of Premalignant Nodules in Hepatocellular Carcinoma on Cirrhosis
Jean Charles Nault et al.
HEPATOLOGY (2014)
Break-Induced Replication Repair of Damaged Forks Induces Genomic Duplications in Human Cells
Lorenzo Costantino et al.
SCIENCE (2014)
Detection of a Recurrent DNAJB1-PRKACA Chimeric Transcript in Fibrolamellar Hepatocellular Carcinoma
Joshua N. Honeyman et al.
SCIENCE (2014)
BRCA1 haploinsufficiency for replication stress suppression in primary cells
Shailja Pathania et al.
NATURE COMMUNICATIONS (2014)
Migrating bubble during break-induced replication drives conservative DNA synthesis
Natalie Saini et al.
NATURE (2013)
Synthetic lethality between CCNE1 amplification and loss of BRCA1
Dariush Etemadmoghadam et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
A Distinct Replication Fork Protection Pathway Connects Fanconi Anemia Tumor Suppressors to RAD51-BRCA1/2
Katharina Schlacher et al.
CANCER CELL (2012)
Systemic Elevation of PTEN Induces a Tumor-Suppressive Metabolic State
Isabel Garcia-Cao et al.
CELL (2012)
The Life History of 21 Breast Cancers
Serena Nik-Zainal et al.
CELL (2012)
An integrated encyclopedia of DNA elements in the human genome
Ian Dunham et al.
NATURE (2012)
Whole-genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators
Akihiro Fujimoto et al.
NATURE GENETICS (2012)
Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma
Wing-Kin Sung et al.
NATURE GENETICS (2012)
Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma
Cecile Guichard et al.
NATURE GENETICS (2012)
Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks
Cole Trapnell et al.
NATURE PROTOCOLS (2012)
Recurrent Targeted Genes of Hepatitis B Virus in the Liver Cancer Genomes Identified by a Next-Generation Sequencing-Based Approach
Dong Ding et al.
PLOS GENETICS (2012)
Integrated genomic analyses of ovarian carcinoma
D. Bell et al.
NATURE (2011)
Integrative genomics viewer
James T. Robinson et al.
NATURE BIOTECHNOLOGY (2011)
Inverted genomic segments and complex triplication rearrangements are mediated by inverted repeats in the human genome
Claudia M. B. Carvalho et al.
NATURE GENETICS (2011)
A framework for variation discovery and genotyping using next-generation DNA sequencing data
Mark A. DePristo et al.
NATURE GENETICS (2011)
A cell-based screen identifies ATR inhibitors with synthetic lethal properties for cancer-associated mutations
Luis I. Toledo et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2011)
The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data
Aaron McKenna et al.
GENOME RESEARCH (2010)
Signatures of mutation and selection in the cancer genome
Graham R. Bignell et al.
NATURE (2010)
The Sequence Alignment/Map format and SAMtools
Heng Li et al.
BIOINFORMATICS (2009)
Fast and accurate short read alignment with Burrows-Wheeler transform
Heng Li et al.
BIOINFORMATICS (2009)
A Microhomology-Mediated Break-Induced Replication Model for the Origin of Human Copy Number Variation
P. J. Hastings et al.
PLOS GENETICS (2009)
E2F1 inhibits c-Myc-driven apoptosis via PIK3CA/Akt/mTOR and COX-2 in a mouse model of human liver cancer
Sara Ladu et al.
GASTROENTEROLOGY (2008)
Sorafenib in advanced hepatocellular carcinoma
Josep M. Llovet et al.
NEW ENGLAND JOURNAL OF MEDICINE (2008)
A DNA replication mechanism for generating nonrecurrent rearrangements associated with genomic disorders
Jennifer A. Lee et al.
CELL (2007)
Template switching during break-induced replication
Catherine E. Smith et al.
NATURE (2007)
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
A Subramanian et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
The n-terminal regulatory domain of cyclin A contains redundant ubiquitination targeting sequences and acceptor sites
TK Fung et al.
CELL CYCLE (2005)
Circular binary segmentation for the analysis of array-based DNA copy number data
AB Olshen et al.
BIOSTATISTICS (2004)
Acute mutation of retinoblastoma gene function is sufficient for cell cycle re-entry
J Sage et al.
NATURE (2003)
Anaphase-promoting complex/cyclosome-dependent proteolysis of human cyclin a starts at the beginning of mitosis and is not subject to the spindle assembly checkpoint
S Geley et al.
JOURNAL OF CELL BIOLOGY (2001)
Prediction whether a human cDNA sequence contains initiation codon by combining statistical information and similarity with protein sequences
T Nishikawa et al.
BIOINFORMATICS (2000)
Dual functions of E2F-1 in a transgenic mouse model of liver carcinogenesis
EA Conner et al.
ONCOGENE (2000)