相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。The Multifaceted Role of STAT3 in Mammary Gland Involution and Breast Cancer
Katherine Hughes et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
Targeting the IL-6/JAK/STAT3 signalling axis in cancer
Daniel E. Johnson et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2018)
Antagonizing STAT3 activation with benzo[b]thiophene 1, 1-dioxide based small molecules
Wenda Zhang et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2017)
Constitutive activation of STAT3 in breast cancer cells: A review
Kasturi Banerjee et al.
INTERNATIONAL JOURNAL OF CANCER (2016)
Small-molecule inhibitors targeting the DNA-binding domain of STAT3 suppress tumor growth, metastasis and STAT3 target gene expression in vivo
W. Huang et al.
ONCOGENE (2016)
Discovery of oral-available resveratrol-caffeic acid based hybrids inhibiting acetylated and phosphorylated STAT3 protein
Shanshan Li et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2016)
Design, synthesis and evaluation of XZH-5 analogues as STAT3 inhibitors
Philias Daka et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2015)
Discovery of a small-molecule inhibitor of STAT3 by ligand-based pharmacophore screening
Ka-Ho Leung et al.
METHODS (2015)
Cryptotanshinone, a Stat3 inhibitor, suppresses colorectal cancer proliferation and growth in vitro
Weidong Li et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2015)
Obatoclax analog SC-2001 inhibits STAT3 phosphorylation through enhancing SHP-1 expression and induces apoptosis in human breast cancer cells
Chun-Yu Liu et al.
BREAST CANCER RESEARCH AND TREATMENT (2014)
Discovery of potent anticancer agent HJC0416, an orally bioavailable small molecule inhibitor of signal transducer and activator of transcription 3 (STAT3)
Haijun Chen et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2014)
Dithiaarsanes Induce Oxidative Stress-Mediated Apoptosis in HL-60 Cells by Selectively Targeting Thioredoxin Reductase
Yaping Liu et al.
JOURNAL OF MEDICINAL CHEMISTRY (2014)
XPO1 ( CRM1) Inhibition Represses STAT3 Activation to Drive a Survivin-Dependent Oncogenic Switch in Triple-Negative Breast Cancer
Yan Cheng et al.
MOLECULAR CANCER THERAPEUTICS (2014)
A Novel Inhibitor of STAT3 Homodimerization Selectively Suppresses STAT3 Activity and Malignant Transformation
Xiaolei Zhang et al.
CANCER RESEARCH (2013)
Fragment-based drug design and identification of HJC0123, a novel orally bioavailable STAT3 inhibitor for cancer therapy
Haijun Chen et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2013)
Discovery of Novel STAT3 Small Molecule Inhibitors via in Silico Site-Directed Fragment-Based Drug Design
Wenying Yu et al.
JOURNAL OF MEDICINAL CHEMISTRY (2013)
Inhibiting Aberrant Signal Transducer and Activator of Transcription Protein Activation with Tetrapodal, Small Molecule Src Homology 2 Domain Binders: Promising Agents against Multiple Myeloma
Brent D. G. Page et al.
JOURNAL OF MEDICINAL CHEMISTRY (2013)
TCPTP Regulates SFK and STAT3 Signaling and Is Lost in Triple-Negative Breast Cancers
Benjamin J. Shields et al.
MOLECULAR AND CELLULAR BIOLOGY (2013)
Discovery of O-Alkylamino-Tethered Niclosamide Derivatives as Potent and Orally Bioavailable Anticancer Agents
Haijun Chen et al.
ACS MEDICINAL CHEMISTRY LETTERS (2013)
Potent Targeting of the STAT3 Protein in Brain Cancer Stem Cells: A Promising Route for Treating Glioblastoma
Sina Haftchenary et al.
ACS MEDICINAL CHEMISTRY LETTERS (2013)
Anti-AIDS agents 85. Design, synthesis, and evaluation of 1R,2R-dicamphanoyl-3,3-dimethyldihydropyrano-[2,3-c]xanthen-7(1H)-one (DCX) derivatives as novel anti-HIV agents
Ting Zhou et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2012)
Antitumor agents 292. Design, synthesis and pharmacological study of S- and O-substituted 7-mercapto- or hydroxy-coumarins and chromones as potent cytotoxic agents
Ying Chen et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2012)
Conditional deletion of Stat3 in mammary epithelium impairs the acute phase response and modulates immune cell numbers during post-lactational regression
Katherine Hughes et al.
JOURNAL OF PATHOLOGY (2012)
Orally bioavailable small-molecule inhibitor of transcription factor Stat3 regresses human breast and lung cancer xenografts
Xiaolei Zhang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Novel small molecule, XZH-5, inhibits constitutive and interleukin-6-induced STAT3 phosphorylation in human rhabdomyosarcoma cells
Aiguo Liu et al.
CANCER SCIENCE (2011)
Oral administration of penta-O-galloyl-β-D-glucose suppresses triple-negative breast cancer xenograft growth and metastasis in strong association with JAK1-STAT3 inhibition
Hyo-Jeong Lee et al.
CARCINOGENESIS (2011)
Anti-AIDS agents 86. Synthesis and anti-HIV evaluation of 2′,3′-seco-3′-nor DCP and DCK analogues
Ying Chen et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2011)
Fragment-Based Drug Design and Drug Repositioning Using Multiple Ligand Simultaneous Docking (MLSD): Identifying Celecoxib and Template Compounds as Novel Inhibitors of Signal Transducer and Activator of Transcription 3 (STAT3)
Huameng Li et al.
JOURNAL OF MEDICINAL CHEMISTRY (2011)
Antitumor Agents 288: Design, Synthesis, SAR, and Biological Studies of Novel Heteroatom-Incorporated Antofine and Cryptopleurine Analogues as Potent and Selective Antitumor Agents
Xiaoming Yang et al.
JOURNAL OF MEDICINAL CHEMISTRY (2011)
A novel small-molecule disrupts Stat3 SH2 domain-phosphotyrosine interactions and Stat3-dependent tumor processes
Xiaolei Zhang et al.
BIOCHEMICAL PHARMACOLOGY (2010)
An unnatural amino acid that mimics phosphotyrosine
Jingyan Ge et al.
CHEMICAL COMMUNICATIONS (2010)
A Novel Small Molecule, LLL12, Inhibits STAT3 Phosphorylation and Activities and Exhibits Potent Growth-Suppressive Activity in Human Cancer Cells
Li Lin et al.
NEOPLASIA (2010)
LLL-3 inhibits STAT3 activity, suppresses glioblastoma cell growth and prolongs survival in a mouse glioblastoma model
B. Fuh et al.
BRITISH JOURNAL OF CANCER (2009)
Cryptotanshinone Inhibits Constitutive Signal Transducer and Activator of Transcription 3 Function through Blocking the Dimerization in DU145 Prostate Cancer Cells
Dae-Seop Shin et al.
CANCER RESEARCH (2009)
Disruption of Transcriptionally Active Stat3 Dimers with Non-phosphorylated, Salicylic Acid-Based Small Molecules: Potent in vitro and Tumor Cell Activities
Steven Fletcher et al.
CHEMBIOCHEM (2009)
Nature: a vital source of leads for anticancer drug development
G. M. Cragg et al.
PHYTOCHEMISTRY REVIEWS (2009)
Discovery of the catechol structural moiety as a Stat3 SH2 domain inhibitor by virtual screening
Wenshan Hao et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2008)
Inhibition of the signal transducer and activator of transcription-3 (STAT3) signaling pathway by 4-oxo-1-phenyl-1,4-dihydroquinoline-3-carboxylic acid esters
Jun Xu et al.
JOURNAL OF MEDICINAL CHEMISTRY (2008)
An oxazole-based small-molecule Stat3 inhibitor modulates Stat3 stability and processing and induces antitumor cell effects
Khandaker A. Z. Siddiquee et al.
ACS CHEMICAL BIOLOGY (2007)
Stattic: A small-molecule inhibitor of STAT3 activation and dimerization
Jochen Schust et al.
CHEMISTRY & BIOLOGY (2006)
Resveratrol inhibits Src and Stat3 signaling and induces the apoptosis of malignant cells containing activated Stat3 protein
A Kotha et al.
MOLECULAR CANCER THERAPEUTICS (2006)
Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival:: an overview of the randomised trials
O Abe et al.
LANCET (2005)
Targeting STAT3 affects melanoma on multiple fronts
M Kortylewski et al.
CANCER AND METASTASIS REVIEWS (2005)
Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival:: an overview of the randomised trials
O Abe et al.
LANCET (2005)
A low-molecular-weight compound discovered through virtual database screening inhibits Stat3 function in breast cancer cells
H Song et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
分享论文
