4.6 Review

Inside out: the role of nucleocytoplasmic transport in ALS and FTLD

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Multidisciplinary Sciences

Cytoplasmic protein aggregates interfere with nucleocytoplasmic transport of protein and RNA

Andreas C. Woerner et al.

SCIENCE (2016)

Article Clinical Neurology

Old versus New Mechanisms in the Pathogenesis of ALS

Simona Rossi et al.

BRAIN PATHOLOGY (2016)

Review Neurosciences

There has been an awakening: Emerging mechanisms of C9orf72 mutations in FTD/ALS

Aaron D. Gitler et al.

BRAIN RESEARCH (2016)

Article Biochemistry & Molecular Biology

ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure

Saumya Jain et al.

Article Multidisciplinary Sciences

Drosophila screen connects nuclear transport genes to DPR pathology in c9ALS/FTD

Steven Boeynaems et al.

SCIENTIFIC REPORTS (2016)

Article Biochemistry & Molecular Biology

A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation

Avinash Patel et al.

Article Biochemistry & Molecular Biology

Nucleolar stress and impaired stress granule formation contribute to C9orf72 RAN translation-induced cytotoxicity

Zhouteng Tao et al.

HUMAN MOLECULAR GENETICS (2015)

Article Clinical Neurology

Drosha Inclusions Are New Components of Dipeptide-Repeat Protein Aggregates in FTLD-TDP and ALS C9orf72 Expansion Cases

Silvia Porta et al.

JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2015)

Article Cell Biology

Cytoplasmic hGle1A regulates stress granules by modulation of translation

Aditi et al.

MOLECULAR BIOLOGY OF THE CELL (2015)

Article Biochemistry & Molecular Biology

Residue-by-Residue View of In Vitro FUS Granules that Bind the C-Terminal Domain of RNA Polymerase II

Kathleen A. Burke et al.

MOLECULAR CELL (2015)

Article Multidisciplinary Sciences

The C9orf72 repeat expansion disrupts nucleocytoplasmic transport

Ke Zhang et al.

NATURE (2015)

Article Multidisciplinary Sciences

GGGGCC repeat expansion in C9orf72 compromises nucleocytoplasmic transport

Brian D. Freibaum et al.

NATURE (2015)

Article Neurosciences

Haploinsufficiency of TBK1 causes familial ALS and fronto-temporal dementia

Axel Freischmidt et al.

NATURE NEUROSCIENCE (2015)

Article Biochemistry & Molecular Biology

Deleterious mutations in the essential mRNA metabolism factor, hGle1, in amyotrophic lateral sclerosis

Hannah M. Kaneb et al.

HUMAN MOLECULAR GENETICS (2015)

Article Biochemistry & Molecular Biology

Disruption of the Ran System by Cysteine Oxidation of the Nucleotide Exchange Factor RCC1

Mandovi Chatterjee et al.

MOLECULAR AND CELLULAR BIOLOGY (2015)

Article Clinical Neurology

Loss of hnRNPA1 in ALS spinal cord motor neurons with TDP-43-positive inclusions

Hiroyuki Honda et al.

NEUROPATHOLOGY (2015)

Article Neurosciences

Alterations in stress granule dynamics driven by TDP-43 and FUS: a link to pathological inclusions in ALS?

Anais Aulas et al.

FRONTIERS IN CELLULAR NEUROSCIENCE (2015)

Article Biochemistry & Molecular Biology

Compromised paraspeckle formation as a pathogenic factor in FUSopathies

Tatyana A. Shelkovnikova et al.

HUMAN MOLECULAR GENETICS (2014)

Article Multidisciplinary Sciences

C9orf72 nucleotide repeat structures initiate molecular cascades of disease

Aaron R. Haeusler et al.

NATURE (2014)

Review Neurosciences

State of play in amyotrophic lateral sclerosis genetics

Alan E. Renton et al.

NATURE NEUROSCIENCE (2014)

Article Neurosciences

Mutations in the Matrin 3 gene cause familial amyotrophic lateral sclerosis

Janel O. Johnson et al.

NATURE NEUROSCIENCE (2014)

Review Clinical Neurology

The phenotypic variability of amyotrophic lateral sclerosis

Bart Swinnen et al.

NATURE REVIEWS NEUROLOGY (2014)

Article Multidisciplinary Sciences

Partial loss of TDP-43 function causes phenotypes of amyotrophic lateral sclerosis

Chunxing Yang et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

Article Multidisciplinary Sciences

C9orf72 repeat expansions cause neurodegeneration in Drosophila through arginine-rich proteins

Sarah Mizielinska et al.

SCIENCE (2014)

Review Oncology

Targeting nucleocytoplasmic transport in cancer therapy

Richard Hill et al.

ONCOTARGET (2014)

Article Genetics & Heredity

The Tau Tubulin Kinases TTBK1/2 Promote Accumulation of Pathological TDP-43

Nicole F. Liachko et al.

PLOS GENETICS (2014)

Article Genetics & Heredity

Stress Granule-Defective Mutants Deregulate Stress Responsive Transcripts

Xiaoxue Yang et al.

PLOS GENETICS (2014)

Review Biochemistry & Molecular Biology

The Hallmarks of Aging

Carlos Lopez-Otin et al.

Article Biochemistry & Molecular Biology

Eukaryotic Stress Granules Are Cleared by Autophagy and Cdc48/VCP Function

J. Ross Buchan et al.

Review Biochemistry & Molecular Biology

Altered Ribostasis: RNA-Protein Granules in Degenerative Disorders

Mani Ramaswami et al.

Article Medicine, Research & Experimental

Spliceosome integrity is defective in the motor neuron diseases ALS and SMA

Hitomi Tsuiji et al.

EMBO MOLECULAR MEDICINE (2013)

Article Biochemistry & Molecular Biology

Reduction of polyglutamine toxicity by TDP-43, FUS and progranulin in Huntington's disease models

Arnaud Tauffenberger et al.

HUMAN MOLECULAR GENETICS (2013)

Article Biochemistry & Molecular Biology

Decreased number of Gemini of coiled bodies and U12 snRNA level in amyotrophic lateral sclerosis

Tomohiko Ishihara et al.

HUMAN MOLECULAR GENETICS (2013)

Article Biochemical Research Methods

Identification of CRM1-dependent Nuclear Export Cargos Using Quantitative Mass Spectrometry

Ketan Thakar et al.

MOLECULAR & CELLULAR PROTEOMICS (2013)

Article Multidisciplinary Sciences

Identification of Genetic Modifiers of TDP-43 Neurotoxicity in Drosophila

Lihong Zhan et al.

PLOS ONE (2013)

Article Multidisciplinary Sciences

Identification of Novel Stress Granule Components That Are Involved in Nuclear Transport

Hicham Mahboubi et al.

PLOS ONE (2013)

Article Multidisciplinary Sciences

RAN proteins and RNA foci from antisense transcripts in C9ORF72 ALS and frontotemporal dementia

Tao Zu et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Clinical Neurology

Pattern of ubiquilin pathology in ALS and FTLD indicates presence of C9ORF72 hexanucleotide expansion

Johannes Brettschneider et al.

ACTA NEUROPATHOLOGICA (2012)

Review Clinical Neurology

The genetics and neuropathology of frontotemporal lobar degeneration

Anne Sieben et al.

ACTA NEUROPATHOLOGICA (2012)

Article Biochemistry & Molecular Biology

Arginine methylation next to the PY-NLS modulates Transportin binding and nuclear import of FUS

Dorothee Dormann et al.

EMBO JOURNAL (2012)

Article Biochemistry & Molecular Biology

Evaluating the role of the FUS/TLS-related gene EWSR1 in amyotrophic lateral sclerosis

Julien Couthouis et al.

HUMAN MOLECULAR GENETICS (2012)

Article Neurosciences

Contrasting Pathology of the Stress Granule Proteins TIA-1 and G3BP in Tauopathies

Tara Vanderweyde et al.

JOURNAL OF NEUROSCIENCE (2012)

Article Biochemistry & Molecular Biology

Tissue-Specific Alternative Splicing Remodels Protein-Protein Interaction Networks

Jonathan D. Ellis et al.

MOLECULAR CELL (2012)

Article Neurosciences

Divergent roles of ALS-linked proteins FUS/TLS and TDP-43 intersect in processing long pre-mRNAs

Clotilde Lagier-Tourenne et al.

NATURE NEUROSCIENCE (2012)

Article Neurosciences

Subcellular Knockout of Importin β1 Perturbs Axonal Retrograde Signaling

Rotem Ben-Tov Perry et al.

NEURON (2012)

Article Multidisciplinary Sciences

Evolutionary Dynamics of Gene and Isoform Regulation in Mammalian Tissues

Jason Merkin et al.

SCIENCE (2012)

Article Multidisciplinary Sciences

Extremely Long-Lived Nuclear Pore Proteins in the Rat Brain

Jeffrey N. Savas et al.

SCIENCE (2012)

Article Biochemistry & Molecular Biology

Identification of Neuronal RNA Targets of TDP-43-containing Ribonucleoprotein Complexes

Chantelle F. Sephton et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2011)

Article Biochemistry & Molecular Biology

TDP-43 Autoregulation: Implications for Disease

Mauricio Budini et al.

JOURNAL OF MOLECULAR NEUROSCIENCE (2011)

Article Neurosciences

Local RNA Translation at the Synapse and in Disease

Liqun Liu-Yesucevitz et al.

JOURNAL OF NEUROSCIENCE (2011)

Article Multidisciplinary Sciences

Active liquid-like behavior of nucleoli determines their size and shape in Xenopus laevis oocytes

Clifford P. Brangwynne et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Article Multidisciplinary Sciences

A yeast functional screen predicts new candidate ALS disease genes

Julien Couthouis et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Review Neurosciences

TDP-43 and FUS: a nuclear affair

Dorothee Dormann et al.

TRENDS IN NEUROSCIENCES (2011)

Article Biochemistry & Molecular Biology

Identification of importin α1 as a novel constituent of RNA stress granules

Ken Fujimura et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2010)

Article Biochemistry & Molecular Biology

ALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear import

Dorothee Dormann et al.

EMBO JOURNAL (2010)

Review Biochemistry & Molecular Biology

TDP-43 and FUS/TLS: emerging roles in RNA processing and neurodegeneration

Clotilde Lagier-Tourenne et al.

HUMAN MOLECULAR GENETICS (2010)

Article Biochemistry & Molecular Biology

The GeneMANIA prediction server: biological network integration for gene prioritization and predicting gene function

David Warde-Farley et al.

NUCLEIC ACIDS RESEARCH (2010)

Article Clinical Neurology

TARDBP 3'-UTR variant in autopsy-confirmed frontotemporal lobar degeneration with TDP-43 proteinopathy

Michael A. Gitcho et al.

ACTA NEUROPATHOLOGICA (2009)

Article Clinical Neurology

A new subtype of frontotemporal lobar degeneration with FUS pathology

Manuela Neumann et al.

Article Biochemistry & Molecular Biology

Mutant SOD1 impairs axonal transport of choline acetyltransferase and acetylcholine release by sequestering KAP3

Minako Tateno et al.

HUMAN MOLECULAR GENETICS (2009)

Review Biochemistry & Molecular Biology

Molecular Neuropathology of TDP-43 Proteinopathies

Manuela Neumann

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2009)

Article Clinical Neurology

Nuclear Contour Irregularity and Abnormal Transporter Protein Distribution in Anterior Horn Cells in Amyotrophic Lateral Sclerosis

Yoshimi Kinoshita et al.

JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2009)

Article Biochemistry & Molecular Biology

A role for transportin in deposition of TTP to cytoplasmic RNA granules and mRNA decay

Wei-Lun Chang et al.

NUCLEIC ACIDS RESEARCH (2009)

Article Multidisciplinary Sciences

Aberrant cleavage of TDP-43 enhances aggregation and cellular toxicity

Yong-Jie Zhang et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Article Multidisciplinary Sciences

Germline P Granules Are Liquid Droplets That Localize by Controlled Dissolution/Condensation

Clifford P. Brangwynne et al.

SCIENCE (2009)

Article Multidisciplinary Sciences

Mutations in the FUS/TLS Gene on Chromosome 16 Cause Familial Amyotrophic Lateral Sclerosis

T. J. Kwiatkowski et al.

SCIENCE (2009)

Article Genetics & Heredity

TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis

Edor Kabashi et al.

NATURE GENETICS (2008)

Article Multidisciplinary Sciences

TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis

Jemeen Sreedharan et al.

SCIENCE (2008)

Article Biochemistry & Molecular Biology

TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

Tetsuaki Arai et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)

Review Biochemistry & Molecular Biology

Neuronal intermediate filaments and ALS: A new look at an old question

Shangxi Xiao et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2006)

Article Multidisciplinary Sciences

Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

Manuela Neumann et al.

SCIENCE (2006)

Review Neurosciences

Splicing regulation in neurologic disease

Donny D. Licatalosi et al.

NEURON (2006)

Review Clinical Neurology

Frontotemporal dementia

D Neary et al.

LANCET NEUROLOGY (2005)

Review Biochemistry & Molecular Biology

Protein aggregation and neurodegenerative disease

CA Ross et al.

NATURE MEDICINE (2004)

Article Biotechnology & Applied Microbiology

Variation in alternative splicing across human tissues

G Yeo et al.

GENOME BIOLOGY (2004)