期刊
TRENDS IN ENDOCRINOLOGY AND METABOLISM
卷 29, 期 12, 页码 816-819出版社
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tem.2018.09.005
关键词
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Polycystic ovary syndrome (PCOS) development commonly starts with a mismatch between pre- and postnatal weight gain, leading to hepatovisceral fat excess. To escape from such central obesity, girls may accelerate their growth and/or maturation. This homeostatic mechanism is lost upon reaching adult height, and PCOS may ensue. Prevention and/or treatment of PCOS should aim at reducing central fat excess.
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