期刊
TRENDS IN BIOTECHNOLOGY
卷 37, 期 4, 页码 347-357出版社
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tibtech.2018.09.007
关键词
-
资金
- National Science Foundation CAREER [PHY-1151454]
- Direct For Mathematical & Physical Scien
- Division Of Physics [1151454] Funding Source: National Science Foundation
Beautiful images of animal cells cultured on surfaces are ubiquitous in biological research, but these shapes also carry valuable information about the cells and the organism that they came from. Cell morphology is an emergent property of the cellular phenotype as well as of the physiological and signaling state of the cell. Many functional changes in cells cause stereotypical changes in cellular morphology, and some changes in shape can also cause characteristic changes in cellular phenotype. Thus, controlling cell shape through substrate engineering may emerge as another mechanism to modulate cell function for human health. This review summarizes current understanding of the morphology-phenotype connection, and surveys progress in the effort to interpret and control cell morphology.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据