期刊
THERAPIE
卷 74, 期 2, 页码 169-174出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.therap.2018.08.001
关键词
Drugs; Pharmacoepidemiology; Efficacy; Effectiveness; Drug risk; Clinical evaluation; Adverse drug reactions
Clinical evaluation of drugs before approval is based on the experimental design of clinical trial with randomization of drug exposure. Unfortunately, conclusions of clinical trials are necessarily limited to patients included into the trials. It is thus necessary to compare these experimental data coming from clinical trials with the real use of drugs in clinical practice. Pharmacoepidemiology is the study of interactions between drugs and human populations, investigating, in real conditions of life, benefits, risks and use of drugs. Pharmacoepidemiology applies to drugs the methods and/or reasoning of both pharmacology and epidemiology. The development of pharmacoepidemiology should improve the rational drug use. (C) 2018 Societe francaise de pharmacologie et de therapeutique. Published by Elsevier Masson SAS. All rights reserved.
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