期刊
TETRAHEDRON LETTERS
卷 60, 期 2, 页码 175-177出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2018.12.006
关键词
Optical resolution; Chiral alcohols; Chiral magnesium phosphate; Asymmetric addition; Imines
资金
- JSPS
- MEXT
- AMED Platform for Supporting Drug Discovery and Life Science Research
A new catalytic method for separating enantiomers of racemic compounds is proposed. Catalytic asymmetric addition of racemic trans-2-substituted cyclohexanols to imines provided diastereomeric mixtures of aminals, and the subsequent separation of the enantiomers by silica-gel column chromatography and the hydrolysis of the aminals produced the alcohols in an optically active form. (C) 2018 Elsevier Ltd. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据