4.4 Article

Highly enantioselective 1,3-dipolar cycloaddition of imino esters with benzofuranone derivatives catalyzed by thiourea-quaternary ammonium salt

期刊

TETRAHEDRON
卷 74, 期 52, 页码 7485-7494

出版社

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2018.11.025

关键词

Asymmetric cyclization; Quaternary ammonium; Phase-transfer catalysis

资金

  1. Chinese Academy of Sciences [XDB 20020100]
  2. National Natural Science Foundation of China [21272247, 21572247]

向作者/读者索取更多资源

Highly enantioselective 1, 3-dipolar cycloaddition of 2-arylidene-benzofuran- 3(2H)-ones with imino esters catalyzed by thiourea-quaternary ammonium salts has been developed. This reaction provides efficient construction of a range of chiral spiro[benzofuran-2,3'-pyrrolidine] in high yields (up to 99%) and with good enantioselectivities (up to 99% ee) under mild conditions. (C) 2018 Elsevier Ltd. All rights reserved.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.4
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据