期刊
RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES
卷 40, 期 5, 页码 989-997出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/IAE.0000000000002460
关键词
macular intraretinal hemorrhage; retinal arterial macroaneurysm; submacular hemorrhage; subretinal hemorrhage; subretinal injection; tissue plasminogen activator
Purpose: To investigate the clinical course of submacular hemorrhage associated with ruptured retinal arterial macroaneurysm using swept-source optical coherence tomography. Methods: This study included 23 eyes of 23 consecutive patients diagnosed with submacular hemorrhage associated with ruptured retinal arterial macroaneurysm. Cases underwent displacement of submacular hemorrhage (vitrectomy + subretinal injection of tissue plasminogen activator + air tamponade) and were followed up for 6 months after surgery. Localization of the preoperative hemorrhage and its effect on preoperative and postoperative best-corrected visual acuity, central retinal thickness, and continuity of the ellipsoid zone were measured. Results: Macular intraretinal hemorrhage (IRH) was observed in 17 eyes (73.9%, IRH [+] group) and was not observed in 6 eyes (26.1%, IRH [-] group). The IRH (+) group showed worse postoperative best-corrected visual acuity values compared with the IRH (-) group (0.89 +/- 0.47 in logarithm of the minimal angle of resolution units, Snellen equivalent 20/155 and 0.16 +/- 0.23, 20/29, respectively; P < 0.01), smaller central retinal thickness values (97.7 +/- 53.5 mu m, 173.0 +/- 32.3 mu m, respectively; P < 0.01), and a higher rate of ellipsoid zone disruption (100%, 33.3%, respectively; P < 0.01). Conclusion: Patients with preoperative macular IRH showed lower postoperative visual acuity and worse macular contour after submacular hemorrhage displacement compared with patients without macular IRH.
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