4.7 Review

Edit at will: Genotype independent plant transformation in the era of advanced genomics and genome editing

期刊

PLANT SCIENCE
卷 281, 期 -, 页码 186-205

出版社

ELSEVIER IRELAND LTD
DOI: 10.1016/j.plantsci.2019.01.006

关键词

Transformation biology; Morphogenic regulators; Genome editing; Functional genomics; Advanced breeding

资金

  1. US NSF Plant Genome Research Program [1444478]
  2. US DOE BER Grant [DE-SC0018277]
  3. Direct For Biological Sciences
  4. Division Of Integrative Organismal Systems [1444478] Funding Source: National Science Foundation
  5. U.S. Department of Energy (DOE) [DE-SC0018277] Funding Source: U.S. Department of Energy (DOE)

向作者/读者索取更多资源

The combination of advanced genomics, genome editing and plant transformation biology presents a powerful platform for basic plant research and crop improvement. Together these advances provide the tools to identify genes as targets for direct editing as single base pair changes, deletions, insertions and site specific homologous recombination. Recent breakthrough technologies using morphogenic regulators in plant transformation creates the ability to introduce reagents specific toward their identified targets and recover stably transformed and/or edited plants which are genotype independent. These technologies enable the possibility to alter a trait in any variety, without genetic disruption which would require subsequent extensive breeding, but rather to deliver the same variety with one trait changed. Regulatory issues regarding this technology will predicate how broadly these technologies will be implemented. In addition, education will play a crucial role for positive public acceptance. Taken together these technologies comprise a platform for advanced breeding which is an imperative for future world food security.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.7
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据