期刊
ACTA BIOMATERIALIA
卷 41, 期 -, 页码 351-360出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.actbio.2016.05.031
关键词
Biomedical magnesium alloy; Fatigue; Corrosion fatigue; Simulated body fluid
资金
- National Basic Research Program of China (973 Program) [2012CB619102, 2012CB619100]
- National Science Fund for Distinguished Young Scholars [51225101]
- National Natural Science Foundation of China [51431002, 31170909]
- NSFC/RGC Joint Research Scheme [51361165101]
- Beijing Municipal Science and Technology Project [Z141100002814008]
The dynamic loading in human body, along with the corrosive body fluid, presents a great challenge for the practical use of biodegradable magnesium implants. In this study, a high purity magnesium (99.99 wt.%) and two typical promising biodegradable magnesium alloys (binary Mg-1 Ca and ternary Mg-2Zn-0.2Ca) were chosen as the experimental materials. Their dynamic mechanical performances were comparatively evaluated by carrying out fatigue tests in air and in simulated body fluid (SBF). The fatigue strengths of HP-Mg, Mg-1Ca and Mg-2Zn-0.2Ca were all around 90 MPa in air, however, they decreased to 52 MPa, 70 MPa and 68 MPa in SBF at 4 x 10(6) cycles, respectively. The fatigue cracks initiated from the microstructural defects when tested in air, but nucleated from surface corrosion pits when tested in SBF. Cyclic loading significantly increased the corrosion rates of all the experimental materials compared to that in static SBF. Moreover, based on our findings, the fatigue failure processes and interactions between material, corrosion and cyclic loading were systematically discussed.
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