Organocatalyzed Intermolecular Asymmetric Allylic Dearomatization of Both α- and β-Naphthols

The first highly stereoselective intermolecular catalytic asymmetric dearomatization (CADA) of alpha-naphthols through C-C formation and the first asymmetric allylic dearomatization of naphthols by chiral organocatalysis have been achieved. These new and complete atom-economic reactions provide enantioriched alpha- and beta-naphthalenones bearing an all-carbon quaternary center.