期刊
ACS NANO
卷 10, 期 3, 页码 3597-3605出版社
AMER CHEMICAL SOC
DOI: 10.1021/acsnano.5b08067
关键词
micromotors; self-propulsion; motion control; hybrid micromotor; mesoporous silica
类别
资金
- European Union [312483]
- European Research Council under the European Union [311529]
- Alexander von Humboldt Foundation
- ICREA Funding Source: Custom
- European Research Council (ERC) [311529] Funding Source: European Research Council (ERC)
The quest for biocompatible microswimmers powered by compatible fuel and with full motion control over their self propulsion is a long-standing challenge in the field of active matter and microrobotics. Here, we present an active hybrid microcapsule motor based on Janus hollow mesoporous silica microparticles powered by the biocatalytic decomposition of urea at physiological concentrations. The directional self-propelled motion lasts longer than 10 min with an average velocity of up to S body lengths per second. Additionally, we control the velocity of the micromotor by chemically inhibiting and reactivating the enzymatic activity of urease. The incorporation of magnetic material within the Janus structure provides remote magnetic control on the movement direction. Furthermore, the mesoporous/hollow structure can load both small molecules and larger particles up to hundreds of nanometers, making the hybrid micromotor an active and controllable drug delivery microsystem.
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