期刊
NATURE REVIEWS MICROBIOLOGY
卷 17, 期 4, 页码 219-232出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/s41579-018-0136-7
关键词
-
类别
资金
- Genomic Science Program of the US Department of Energy Office of Biological and Environmental Research [DE-FOA-0001458, DE-SC0016440]
- Australian Research Council (ARC) Discovery Early Career Researcher Award [170100428]
- ARC Discovery Early Career Researcher Award [160100248]
- ARC Postgraduate awards
- ARC Laureate Fellowship Award
- University of Queensland Vice Chancellor Research Focused Fellowship
Methane is a key compound in the global carbon cycle that influences both nutrient cycling and the Earth's climate. A limited number of microorganisms control the flux of biologically generated methane, including methane-metabolizing archaea that either produce or consume methane. Methanogenic and methanotrophic archaea belonging to the phylum Euryarchaeota share a genetically similar, interrelated pathway for methane metabolism. The key enzyme in this pathway, the methyl-coenzyme M reductase (Mcr) complex, catalyses the last step in methanogenesis and the first step in methanotrophy. The discovery of mcr and divergent mcr-like genes in new euryarchaeotal lineages and novel archaeal phyla challenges long-held views of the evolutionary origin of this metabolism within the Euryarchaeota. Divergent mcr-like genes have recently been shown to oxidize short-chain alkanes, indicating that these complexes have evolved to metabolize substrates other than methane. In this Review, we examine the diversity, metabolism and evolutionary history of mcr-containing archaea in light of these recent discoveries.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据