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Julian Nuechel et al.
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Transcriptional network systems in cartilage development and disease
Riko Nishimura et al.
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Genome-wide analyses using UK Biobank data provide insights into the genetic architecture of osteoarthritis
Eleni Zengini et al.
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Gibran Hemani et al.
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Myung-Ku Kim et al.
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LD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis
Jie Zheng et al.
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Open Targets: a platform for therapeutic target identification and validation
Gautier Koscielny et al.
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Julia Steinberg et al.
SCIENTIFIC REPORTS (2017)
Genome-wide analysis of health-related biomarkers in the UK Household Longitudinal Study reveals novel associations
Bram P. Prins et al.
SCIENTIFIC REPORTS (2017)
STOPGAP: a database for systematic target opportunity assessment by genetic association predictions
Judong Shen et al.
BIOINFORMATICS (2017)
Orthopedic Manifestations of Type I Camurati-Engelmann Disease
Alisher J. Yuldashev et al.
CLINICS IN ORTHOPEDIC SURGERY (2017)
A Pleiotropic Missense Variant in SLC39A8 Is Associated With Crohn's Disease and Human Gut Microbiome Composition
Dalin Li et al.
GASTROENTEROLOGY (2016)
A blood pressure-associated variant of the SLC39A8 gene influences cellular cadmium accumulation and toxicity
Ruoxin Zhang et al.
HUMAN MOLECULAR GENETICS (2016)
A reference panel of 64,976 haplotypes for genotype imputation
Shane McCarthy et al.
NATURE GENETICS (2016)
Genetic Determinism of Primary Early-Onset Osteoarthritis
Juliette Aury-Landas et al.
TRENDS IN MOLECULAR MEDICINE (2016)
TGF-β and BMP signaling in osteoblast, skeletal development, and bone formation, homeostasis and disease
Mengrui Wu et al.
BONE RESEARCH (2016)
The Genotype-Tissue Expression (GTEx) Project
Latarsha J. Carithers et al.
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A global reference for human genetic variation
David M. Altshuler et al.
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An atlas of genetic correlations across human diseases and traits
Brendan Bulik-Sullivan et al.
NATURE GENETICS (2015)
LD Score regression distinguishes confounding from polygenicity in genome-wide association studies
Brendan K. Bulik-Sullivan et al.
NATURE GENETICS (2015)
Insights into osteoarthritis progression revealed by analyses of both knee tibiofemoral compartments
C. -H. Chou et al.
OSTEOARTHRITIS AND CARTILAGE (2015)
The Genotype-Tissue Expression (GTEx) Project
Latarsha J. Carithers et al.
BIOPRESERVATION AND BIOBANKING (2015)
MAGMA: Generalized Gene-Set Analysis of GWAS Data
Christiaan A. de Leeuw et al.
PLOS COMPUTATIONAL BIOLOGY (2015)
UK Biobank: An Open Access Resource for Identifying the Causes of a Wide Range of Complex Diseases of Middle and Old Age
Cathie Sudlow et al.
PLOS MEDICINE (2015)
Genetic and epigenetic fine mapping of causal autoimmune disease variants
Kyle Kai-How Farh et al.
NATURE (2015)
A meta-analysis of genome-wide association studies identifies novel variants associated with osteoarthritis of the hip
Evangelos Evangelou et al.
ANNALS OF THE RHEUMATIC DISEASES (2014)
Regulation of the Catabolic Cascade in Osteoarthritis by the Zinc-ZIP8-MTF1 Axis
Jin-Hong Kim et al.
CELL (2014)
MicroRNA-146a Regulates Human Foetal Femur Derived Skeletal Stem Cell Differentiation by Down-Regulating SMAD2 and SMAD3
Kelvin S. C. Cheung et al.
PLOS ONE (2014)
Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics
Claudia Giambartolomei et al.
PLOS GENETICS (2014)
Health economics in the field of osteoarthritis: An Expert's consensus paper from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO)
Mickael Hiligsmann et al.
SEMINARS IN ARTHRITIS AND RHEUMATISM (2013)
NFAT3 and TGF-β/SMAD3 regulate the expression of miR-140 in osteoarthritis
Ginette Tardif et al.
ARTHRITIS RESEARCH & THERAPY (2013)
MicroRNA-488 regulates zinc transporter SLC39A8/ZIP8 during pathogenesis of osteoarthritis
Jinsoo Song et al.
JOURNAL OF BIOMEDICAL SCIENCE (2013)
Evaluating the effective numbers of independent tests and significant p-value thresholds in commercial genotyping arrays and public imputation reference datasets
Miao-Xin Li et al.
HUMAN GENETICS (2012)
The effect of surgical factors on early patient-reported outcome measures (PROMS) following total knee replacement
P. N. Baker et al.
JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME (2012)
Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study
Eleftheria Zeggini et al.
LANCET (2012)
Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010
Theo Vos et al.
LANCET (2012)
Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height
Matthew B. Lanktree et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2011)
GCTA: A Tool for Genome-wide Complex Trait Analysis
Jian Yang et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2011)
Insights into the genetic architecture of osteoarthritis from stage 1 of the arcOGEN study
K. Panoutsopoulou et al.
ANNALS OF THE RHEUMATIC DISEASES (2011)
TGF-β Regulates β-Catenin Signaling and Osteoblast Differentiation in Human Mesenchymal Stem Cells
Shuanhu Zhou
JOURNAL OF CELLULAR BIOCHEMISTRY (2011)
METAL: fast and efficient meta-analysis of genomewide association scans
Cristen J. Willer et al.
BIOINFORMATICS (2010)
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index
Elizabeth K. Speliotes et al.
NATURE GENETICS (2010)
Bayes Factors for Genome-Wide Association Studies: Comparison with P-values
Jon Wakefield
GENETIC EPIDEMIOLOGY (2009)
TGF-β1-induced migration of bone mesenchymal stem cells couples bone resorption with formation
Yi Tang et al.
NATURE MEDICINE (2009)
Latent TGF-β binding proteins (LTBPs)-1 and -3 coordinate proliferation and osteogenic differentiation of human mesenchymal stem cells
Katri Koli et al.
BONE (2008)
PLINK: A tool set for whole-genome association and population-based linkage analyses
Shaun Purcell et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2007)
Camurati-Engelmann disease: review of the clinical, radiological, and molecular data of 24 families and implications for diagnosis and treatment
K Janssens et al.
JOURNAL OF MEDICAL GENETICS (2006)
Interleukin-11 receptor signaling is required for normal bone remodeling
NA Sims et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2005)
Cooperation between TGF-β and Wnt pathways during chondrocyte and adipocyte differentiation of human marrow stromal cells
SH Zhou et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2004)
Characterization of a potent human interleukin-11 agonist
D Harmegnies et al.
BIOCHEMICAL JOURNAL (2003)
Interleukin-11 as a stimulatory factor for bone formation prevents bone loss with advancing age in mice
Y Takeuchi et al.
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TGF-β/Smad3 signals repress chondrocyte hypertrophic differentiation and are required for maintaining articular cartilage
X Yang et al.
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