期刊
ACS NANO
卷 10, 期 11, 页码 10389-10396出版社
AMER CHEMICAL SOC
DOI: 10.1021/acsnano.6b06256
关键词
transient; micromotor; biocompatible; controlled degradation
类别
资金
- Defense Threat Reduction Agency Joint Science and Technology Office for Chemical and Biological Defense [HDTRA1-13-1-0002, HDTRA1-14-1-0064]
- National Natural Science Foundation of China [21474078, 51521001]
- Charles Lee Powell Foundation
- University of California, San Diego
- China Scholarship Council (CSC)
Transient self-destroyed micromotors that autonomously disappear in biological media at controlled rates upon completing their task, without leaving a toxic residue, are presented. The propulsion and degradation characteristics of the self-destroyed Mg/ZnO, Mg/Si, and Zn/Fe Janus micromotors and single component Zn micromotors are described. The degradation of the Janus micromotors relies on the different corrosion rates of their core shell components. Inductively coupled plasma optical emission spectrometry measurements are used to probe the time-dependent degradation of the different constituents of the micromotors. The toxicity of the transient micromotors is discussed toward their potential use in biomedical applications. This concept of transient micromotors offers considerable potential for diverse practical applications in the near future.
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