期刊
MOLECULAR DIVERSITY
卷 23, 期 3, 页码 739-749出版社
SPRINGER
DOI: 10.1007/s11030-018-9907-3
关键词
Magnetite nanocatalyst; Ciprofloxacin; Isocyanide-based multicomponent reactions; 1H-Chromeno[2; 3-d]pyrimidine-5-carboxamides; Imidazo[1; 2-a]pyridines
类别
资金
- Iran National Science Foundation (INSF)
- Research Council of Razi University
In this research, synthesis and characterization of new surface-functionalized magnetic silica nanoparticles are reported. The magnetic silica nanoparticle was synthesized by a silica coating of the magnetite nanoparticles through a sol-gel process, and then, their surface was modified by (3-chloropropyl)triethoxysilane and covalently functionalized by ciprofloxacin. The catalyst activity of prepared functionalized nanoparticle was investigated by isocyanide-based multicomponent reactions for the synthesis of 1H-chromeno[2,3-d]pyrimidine-5-carboxamides and imidazo[1,2-a]pyridines. This catalyst was recycled by magnetic filtration and reprocessed five times without having a significant loss of catalytic activity. [GRAPHICS] .
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