期刊
MOLECULAR CELL
卷 72, 期 3, 页码 404-412出版社
CELL PRESS
DOI: 10.1016/j.molcel.2018.09.018
关键词
-
资金
- NIH [R35GM118160]
DNA-targeting CRISPR-Cas systems, such as those employing the RNA-guided Cas9 or Cas12 endonucleases, have revolutionized our ability to predictably edit genomes and control gene expression. Here, I summarize information on RNA-targeting CRISPR-Cas systems and describe recent advances in converting them into powerful and programmable RNA-binding and cleavage tools with a wide range of novel and important biotechnological and biomedical applications.
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