相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Identification of a novel selective small-molecule inhibitor of protein arginine methyltransferase 5 (PRMT5) by virtual screening, resynthesis and biological evaluations
Kongkai Zhu et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2018)
Protein arginine methyltransferase 5 promotes lung cancer metastasis via the epigenetic regulation of miR-99 family/FGFR3 signaling
Pengyu Jing et al.
CANCER LETTERS (2018)
Specificity Protein Transcription Factors and Cancer: Opportunities for Drug Development
Stephen Safe et al.
CANCER PREVENTION RESEARCH (2018)
Protein kinase C: perfectly balanced
Alexandra C. Newton
CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY (2018)
Curcumin: A Natural Pan-HDAC Inhibitor in Cancer
Sara Saffar Soflaei et al.
CURRENT PHARMACEUTICAL DESIGN (2018)
Identification of Selective, Cell Active Inhibitors of Protein Arginine Methyltransferase 5 through Structure-Based Virtual Screening and Biological Assays
Fei Ye et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2018)
Expression of protein arginine methyltransferase-5 in oral squamous cell carcinoma and its significance in epithelial-to-mesenchymal transition
Yusuke Amano et al.
PATHOLOGY INTERNATIONAL (2018)
Protein kinase C (PKC) isoforms in cancer, tumor promotion and tumor suppression
Noah Isakov
SEMINARS IN CANCER BIOLOGY (2018)
PRMT5 promotes cell proliferation by inhibiting BTG2 expression via the ERK signaling pathway in hepatocellular carcinoma
Hai Jiang et al.
CANCER MEDICINE (2018)
Discovery of selective protein arginine methyltransferase 5 inhibitors and biological evaluations
Sen Ji et al.
CHEMICAL BIOLOGY & DRUG DESIGN (2017)
A TGFβ-PRMT5-MEP50 axis regulates cancer cell invasion through histone H3 and H4 arginine methylation coupled transcriptional activation and repression
H. Chen et al.
ONCOGENE (2017)
Protein arginine methyltransferase 5 functions as an epigenetic activator of the androgen receptor to promote prostate cancer cell growth
X. Deng et al.
ONCOGENE (2017)
Targeting protein arginine methyltransferase 5 in disease
Andre Richters
FUTURE MEDICINAL CHEMISTRY (2017)
The protein arginine methyltransferase 5 promotes malignant phenotype of hepatocellular carcinoma cells and is associated with adverse patient outcomes after curative hepatectomy
Dai Shimizu et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2017)
Potent, Selective, and Cell Active Protein Arginine Methyltransferase 5 (PRMT5) Inhibitor Developed by Structure-Based Virtual Screening and Hit Optimization
Ruifeng Mao et al.
JOURNAL OF MEDICINAL CHEMISTRY (2017)
Arginine Methylation: The Coming of Age
Romeo S. Blanc et al.
MOLECULAR CELL (2017)
Selective small-chemical inhibitors of protein arginine methyltransferase 5 with anti-lung cancer activity
Gui-Mei Kong et al.
PLOS ONE (2017)
Targeting multiple pro-apoptotic signaling pathways with curcumin in prostate cancer cells
Mariela Rivera et al.
PLOS ONE (2017)
Curcumin: A Review of Its Effects on Human Health
Susan J. Hewlings et al.
FOODS (2017)
NF-Y in cancer: Impact on cell transformation of a gene essential for proliferation
Aymone Gurtner et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS (2017)
Targeting PI3K Signaling in Combination Cancer Therapy
Elvire Pons-Tostivint et al.
TRENDS IN CANCER (2017)
NF-Y and SP transcription factors-New insights in a long-standing liaison
Guntram Suske
BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS (2017)
Akt inhibitors in cancer treatment: The long journey from drug discovery to clinical use
George Mihai Nitulescu et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2016)
Biochemistry and regulation of the protein arginine methyltransferases (PRMTs)
Yalemi Morales et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2016)
Polyphenol compounds and PKC signaling
Joydip Das et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2016)
Protein arginine methyltransferase 5 regulates multiple signaling pathways to promote lung cancer cell proliferation
Xiumei Sheng et al.
BMC CANCER (2016)
Specificity protein (Sp) transcription factors Sp1, Sp3 and Sp4 are non-oncogene addiction genes in cancer cells
Erik Hedrick et al.
ONCOTARGET (2016)
The PRMT5 arginine methyltransferase: many roles in development, cancer and beyond
Nicole Stopa et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2015)
Sp1 and the 'hallmarks of cancer'
Kate Beishline et al.
FEBS JOURNAL (2015)
Histone H2A and H4 N-terminal Tails Are Positioned by the MEP50 WD Repeat Protein for Efficient Methylation by the PRMT5 Arginine Methyltransferase
Emmanuel S. Burgos et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
PI3K/AKT signaling pathway and cancer: an updated review
Miriam Martini et al.
ANNALS OF MEDICINE (2014)
Transcriptional activation of PRMT5 by NF-Y is required for cell growth and negatively regulated by the PKC/c-Fos signaling in prostate cancer cells
Huan-Tian Zhang et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS (2014)
Sequence-Specific Transcription Factor NF-Y Displays Histone-like DNA Binding and H2B-like Ubiquitination
Marco Nardini et al.
CELL (2013)
Overexpression of PRMT5 Promotes Tumor Cell Growth and Is Associated with Poor Disease Prognosis in Epithelial Ovarian Cancer
Xiangxiang Bao et al.
JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY (2013)
Curcumin Down-Regulates DNA Methyltransferase 1 and Plays an Anti-Leukemic Role in Acute Myeloid Leukemia
Jianhua Yu et al.
PLOS ONE (2013)
PRMT5 Is Upregulated in Malignant and Metastatic Melanoma and Regulates Expression of MITF and p27Kip1
Courtney Nicholas et al.
PLOS ONE (2013)
Concurrent inhibition of enzymatic activity and NF-Y-mediated transcription of Topoisomerase-IIα by bis-DemethoxyCurcumin in cancer cells
S. Belluti et al.
CELL DEATH & DISEASE (2013)
Protein arginine methyltransferase 5 is essential for growth of lung cancer cells
Zhongping Gu et al.
BIOCHEMICAL JOURNAL (2012)
HOXA9 Methylation by PRMT5 Is Essential for Endothelial Cell Expression of Leukocyte Adhesion Molecules
Smarajit Bandyopadhyay et al.
MOLECULAR AND CELLULAR BIOLOGY (2012)
NIH Image to ImageJ: 25 years of image analysis
Caroline A. Schneider et al.
NATURE METHODS (2012)
Pharmacodynamics of curcumin as DNA hypomethylation agent in restoring the expression of Nrf2 via promoter CpGs demethylation
Tin Oo Khor et al.
BIOCHEMICAL PHARMACOLOGY (2011)
Crosstalk between Arg 1175 methylation and Tyr 1173 phosphorylation negatively modulates EGFR-mediated ERK activation
Jung-Mao Hsu et al.
NATURE CELL BIOLOGY (2011)
Specific inhibition of NF-Y subunits triggers different cell proliferation defects
Paolo Benatti et al.
NUCLEIC ACIDS RESEARCH (2011)
Protein Arginine Methyltransferase 5 Regulates ERK1/2 Signal Transduction Amplitude and Cell Fate Through CRAF
Pedro Andreu-Perez et al.
SCIENCE SIGNALING (2011)
Versatility of PRMT5-induced methylation in growth control and development
Vrajesh Karkhanis et al.
TRENDS IN BIOCHEMICAL SCIENCES (2011)
Specificity protein, Sp1-mediated increased expression of Prdx6 as a curcumin-induced antioxidant defense in lens epithelial cells against oxidative stress
B. Chhunchha et al.
CELL DEATH & DISEASE (2011)
PRMT5 regulates Golgi apparatus structure through methylation of the golgin GM130
Zhongwei Zhou et al.
CELL RESEARCH (2010)
Curcumin induces down-regulation of EZH2 expression through the MAPK pathway in MDA-MB-435 human breast cancer cells
Wen-Feng Hua et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2010)
Inhibition of NFκB and Pancreatic Cancer Cell and Tumor Growth by Curcumin Is Dependent on Specificity Protein Down-regulation
Indira Jutooru et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Curcumin is a potent DNA hypomethylation agent
Zhongfa Liu et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2009)
Curcumin induces apoptosis-independent death in oesophageal cancer cells
G. O'Sullivan-Coyne et al.
BRITISH JOURNAL OF CANCER (2009)
Expression levels of NF-Y target genes changed by CDKN1B correlate with clinical prognosis in multiple cancers
Kazunori Yamanaka et al.
GENOMICS (2009)
PRMT5-mediated methylation of histone H4R3 recruits DNMT3A, coupling histone and DNA methylation in gene silencing
Quan Zhao et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2009)
Curcumin: Preventive and therapeutic properties in laboratory studies and clinical trials
Alexios S. Strimpakos et al.
ANTIOXIDANTS & REDOX SIGNALING (2008)
Curcumin decreases specificity protein expression in bladder cancer cells
Gayathri Chadalapaka et al.
CANCER RESEARCH (2008)
The histone-binding protein COPR5 is required for nuclear functions of the protein arginine methyltransferase PRMT5
Matthieu Lacroix et al.
EMBO REPORTS (2008)
Protein arginine methyltransferase 5 suppresses the transcription of the RB family of tumor suppressors in leukemia and lymphoma cells
Li Wang et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
Matlnspector and beyond: promoter analysis based on transcription factor binding sites
K Cartharius et al.
BIOINFORMATICS (2005)
Curcumin, a novel p300/CREB-binding protein-specific inhibitor of acetyltransferase, represses the acetylation of histone/nonhistone proteins and histone acetyltransferase-dependent chromatin transcription
K Balasubramanyam et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Human SWI/SNF-associated PRMT5 methylates histone H3 arginine 8 and negatively regulates expression of ST7 and NM23 tumor suppressor genes
S Pal et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Transcriptional regulation of the human Sp1 gene promoter by the specificity protein (Sp) family members nuclear factor Y (NF-Y) and E2F
M Nicolás et al.
BIOCHEMICAL JOURNAL (2003)
Assisted RNP assembly: SMN and PRMT5 complexes cooperate in the formation of spliceosomal UsnRNPs
G Meister et al.
EMBO JOURNAL (2002)
Negative regulation of transcription by the type II arginine methyltransferase PRMT5
E Fabbrizio et al.
EMBO REPORTS (2002)
Methylation of Sm proteins by a complex containing PRMT5 and the putative U snRNP assembly factor pICln
G Meister et al.
CURRENT BIOLOGY (2001)
PRMT5, which forms distinct homo-oligomers, is a member of the protein-arginine methyltransferase family
J Rho et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Sp family members and nuclear factor-Y cooperatively stimulate transcription from the rat pyruvate kinase M gene distal promoter region via their direct interactions
K Yamada et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)