期刊
MINERVA CHIRURGICA
卷 74, 期 1, 页码 97-106出版社
EDIZIONI MINERVA MEDICA
DOI: 10.23736/S0026-4733.18.07796-9
关键词
Oligometastatic cancer; Prostate cancer; Salvage lymph node dissection; Positron emission tomography; Biochemical recurrence
类别
I NTRODUCTION: We provide a comprehensive description of the physio-pathological theories behind oligometastatic prostate cancer (PCa) and analyze modern imaging techniques, presenting a systematic review of the available evidences regarding salvage lymph node dissection (sLND). EVIDENCE ACQUISITION: A systematic review was attempted. The PubMed/Medline database was searched for salvage AND (lymph node dissection OR lymphadenectomy) AND prostate AND cancer. Only English publications were targeted. Relevant original articles addressing the role of sLND in PCa were selected. EVIDENCE SYNTHESIS: Biochemical response (BR) was reported in 10-79.5% of the cases overall. These results were not durable and biochemical recurrence occurred in 54.5-93.8% of the cases, within 5 years. Furthermore, 50-80% of patients received some kind of adjuvant treatment right after sLND, regardless post-operative prostate-specific antigen levels. Surgery-related morbidity was low, with a 0-27% incidence of Clavien-Dindo III complications. No sLND-related deaths were observed. CONCLUSIONS: sLND is not associated with a durable response over time but may postpone HT and its related complications, in selected patients. Although a limited morbidity was reported, sLND remains technically demanding and a careful selection of patients is advisable.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据