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Masood A. Shammas
CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE (2011)
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Spermidine and resveratrol induce autophagy by distinct pathways converging on the acetylproteome
Eugenia Morselli et al.
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Nadine Saul et al.
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Dietary Epicatechin Promotes Survival of Obese Diabetic Mice and Drosophila melanogaster
Hongwei Si et al.
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Richard A. Miller et al.
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Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
Darren J. Baker et al.
NATURE (2011)
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Vivian Hsiu-Chuan Liao et al.
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Jing X. Kang
NUTRITION (2011)
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Tsuyoshi Tsuduki et al.
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L-X. Na et al.
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Liver-Derived IGF-I Regulates Mean Life Span in Mice
Johan Svensson et al.
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Mitsuharu Matsumoto et al.
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Icariin and its Derivative Icariside II Extend Healthspan via Insulin/IGF-1 Pathway in C. elegans
Wai-Jiao Cai et al.
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FDA-Approved Drugs that Protect Mammalian Neurons from Glucose Toxicity Slow Aging Dependent on Cbp and Protect Against Proteotoxicity
Alex Lublin et al.
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Tony Tiganis
TRENDS IN PHARMACOLOGICAL SCIENCES (2011)
SRT1720 improves survival and healthspan of obese mice
Robin K. Minor et al.
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Igho Onakpoya et al.
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Total mortality risk in relation to use of less-common dietary supplements
Gaia Pocobelli et al.
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Resveratrol attenuates 6-hydroxydopamine-induced oxidative damage and dopamine depletion in rat model of Parkinson's disease
Mohd. Moshahid Khan et al.
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SIRT1 Promotes Proliferation and Prevents Senescence Through Targeting LKB1 in Primary Porcine Aortic Endothelial Cells
Yi Zu et al.
CIRCULATION RESEARCH (2010)
Resveratrol inhibits right ventricular hypertrophy induced by monocrotaline in rats
Dan-Li Yang et al.
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY (2010)
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Yoshihito Sakata et al.
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Jun Lu et al.
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Nadine Saul et al.
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Brian Onken et al.
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Shin-ichiro Imai
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Curcumin Extends Life Span, Improves Health Span, and Modulates the Expression of Age-Associated Aging Genes in Drosophila melanogaster
Kyu-Sun Lee et al.
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Luigi Fontana et al.
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Robin K. Minor et al.
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Caloric restriction and resveratrol promote longevity through the Sirtuin-1-dependent induction of autophagy
E. Morselli et al.
CELL DEATH & DISEASE (2010)
The overexpression of major antioxidant enzymes does not extend the lifespan of mice
Viviana I. Perez et al.
AGING CELL (2009)
Quercetin increases brain and muscle mitochondrial biogenesis and exercise tolerance
J. Mark Davis et al.
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Curcumin activates AMPK and suppresses gluconeogenic gene expression in hepatoma cells
Teayoun Kim et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2009)
Quercetin mediated lifespan extension in Caenorhabditis elegans is modulated by age-1, daf-2, sek-1 and unc-43
Kerstin Pietsch et al.
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Miao He et al.
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2009)
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Ming-Hong Chuang et al.
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Epigallocatechin-3-Gallate, a Histone Acetyltransferase Inhibitor, Inhibits EBV-Induced B Lymphocyte Transformation via Suppression of ReIA Acetylation
Kyung-Chul Choi et al.
CANCER RESEARCH (2009)
Glucose Shortens the Life Span of C. elegans by Downregulating DAF-16/FOXO Activity and Aquaporin Gene Expression
Seung-Jae Lee et al.
CELL METABOLISM (2009)
New Users of Metformin Are at Low Risk of Incident Cancer A cohort study among people with type 2 diabetes
Gillian Libby et al.
DIABETES CARE (2009)
Black tea theaflavins extend the lifespan of fruit flies
Cheng Peng et al.
EXPERIMENTAL GERONTOLOGY (2009)
Bioavailability of C-Linked Dihydrochalcone and Flavanone Glucosides in Humans Following Ingestion of Unfermented and Fermented Rooibos Teas
Angelique Stalmach et al.
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Regulation of Autophagy by the p300 Acetyltransferase
In Hye Lee et al.
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Cell Stress and Aging: New Emphasis on Multiplex Resistance Mechanisms
Richard A. Miller
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2009)
Rapamycin fed late in life extends lifespan in genetically heterogeneous mice
David E. Harrison et al.
NATURE (2009)
Induction of autophagy by spermidine promotes longevity
Tobias Eisenberg et al.
NATURE CELL BIOLOGY (2009)
A method for oral administration of hydrophilic substances to Caenorhabditis elegans: Effects of oral supplementation with antioxidants on the nematode lifespan
Ayumi Shibamura et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2009)
Catechin induced longevity in C. elegans: From key regulator genes to disposable soma
Nadine Saul et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2009)
Dietary supplementation with resveratrol reduces plaque pathology in a transgenic model of Alzheimer's disease
Saravanan S. Karuppagounder et al.
NEUROCHEMISTRY INTERNATIONAL (2009)
Epigallocatechin Gallate from Green Tea (Camellia sinensis) Increases Lifespan and Stress Resistance in Caenorhabditis elegans
Sami Abbas et al.
PLANTA MEDICA (2009)
Association of FOXO3A variation with human longevity confirmed in German centenarians
Friederike Flachsbart et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Antioxidants prevent health-promoting effects of physical exercise in humans
Michael Ristow et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
mTOR Regulation and Therapeutic Rejuvenation of Aging Hematopoietic Stem Cells
Chong Chen et al.
SCIENCE SIGNALING (2009)
Remarkable longevity and stress resistance of nematode PI3K-null mutants
Srinivas Ayyadevara et al.
AGING CELL (2008)
Nordihydroguaiaretic acid and aspirin increase lifespan of genetically heterogeneous male mice
Randy Strong et al.
AGING CELL (2008)
Berberine improves glucose metabolism through induction of glycolysis
Jun Yin et al.
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Reserpine can confer stress tolerance and lifespan extension in the nematode C-elegans
Deepti Srivastava et al.
BIOGERONTOLOGY (2008)
Effects of long-term administration of a cocoa polyphenolic extract (Acticoa powder) on cognitive performances in aged rats
Jean-Francois Bisson et al.
BRITISH JOURNAL OF NUTRITION (2008)
Metformin slows down aging and extends life span of female SHR mice
Vladimir N. Anisimov et al.
CELL CYCLE (2008)
SirT1 inhibition reduces IGF-I/IRS-2/Ras/ERK1/2 signaling and protects neurons
Ying Li et al.
CELL METABOLISM (2008)
Stress-response hormesis and aging: That which Does Not Kill Us Makes Us Stronger
David Gems et al.
CELL METABOLISM (2008)
Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span
Kevin J. Pearson et al.
CELL METABOLISM (2008)
AMP-activated protein kinase in skeletal muscle: From structure and localization to its role as a master regulator of cellular metabolism
C. A. Witczak et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2008)
Increase of stress resistance and lifespan of Caenorhabditis elegans by quercetin
Andreas Kampkoetter et al.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY (2008)
Telomerase-Based Pharmacologic Enhancement of Antiviral Function of Human CD8+ T Lymphocytes
Steven Russell Fauce et al.
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Creatine improves health and survival of mice
A. Bender et al.
NEUROBIOLOGY OF AGING (2008)
Aspalathin, a flavonoid in Aspalathus linearis (rooibos), is absorbed by pig intestine as a C-glycoside
Susanne Kreuz et al.
NUTRITION RESEARCH (2008)
FOXO3A genotype is strongly associated with human longevity
Bradley J. Wilicox et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Functionally significant insulin-like growth factor I receptor mutations in centenarians
Yousin Suh et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Metabolic adaptations through the PGC-1α and SIRT1 pathways
Joseph T. Rodgers et al.
FEBS LETTERS (2008)
Anti-obesity effects of ginsenoside Rh2 are associated with the activation of AMPK signaling pathway in 3T3-L1 adipocyte
Jin-Taek Hwang et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
Effects of the flavonoids kaempferol and fisetin on thermotolerance, oxidative stress and FoxO transcription factor DAF-16 in the model organism Caenorhabditis elegans
Andreas Kampkoetter et al.
ARCHIVES OF TOXICOLOGY (2007)
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Jill C. Milne et al.
NATURE (2007)
Theaflavins attenuate hepatic lipid accumulation through activating AMPK in human HepG2 cells
Chih-Li Lin et al.
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Pancreatic lipase inhibitors from natural sources: unexplored potential
Rahul B. Birari et al.
DRUG DISCOVERY TODAY (2007)
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Kenichi Kitani et al.
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The common biology of cancer and ageing
Toren Finkel et al.
NATURE (2007)
Mortality in randomized trials of antioxidant supplements for primary and secondary prevention - Systematic review and meta-analysis
Goran Bjelakovic et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2007)
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Jaemin Jeong et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2007)
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S. Astner et al.
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Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1α
Marie Lagouge et al.
CELL (2006)
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Joseph A. Baur et al.
NATURE (2006)
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Marishka K. Brown et al.
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2006)
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Coleen T. Murphy
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Berberine, a natural plant product, activates AMP-activated protein kinase with beneficial metabolic effects in diabetic and insulin-resistant states
Yun S. Lee et al.
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Masaaki Komatsu et al.
NATURE (2006)
Chronic systemic D-Galactose exposure induces memory loss, neuro degeneration, and oxidative damage in mice:: Protective effects of R-α-lipoic acid
Xu Cui et al.
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G Candore et al.
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Blueberry polyphenols increase lifespan and thermotolerance in Caenorhabditis elegans
MA Wilson et al.
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R Mostoslavsky et al.
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AJ Dirks et al.
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Joseph A. Baur et al.
NATURE REVIEWS DRUG DISCOVERY (2006)
Genistein, EGCG, and capsaicin inhibit adipocyte differentiation process via activating AMP-activated protein kinase
JT Hwang et al.
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Sir2 blocks extreme life-span extension
P Fabrizio et al.
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AM Prentice
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I Flores et al.
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L Li et al.
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A complex dietary supplement extends longevity of mice
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Mahmoud Kiaei et al.
NEURODEGENERATIVE DISEASES (2005)
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A Bartke
ENDOCRINOLOGY (2005)
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A Brunet et al.
SCIENCE (2004)
Coenzyme Q supplementation protects from age-related DNA double-strand breaks and increases lifespan in rats fed on a PUFA-rich diet
JL Quiles et al.
EXPERIMENTAL GERONTOLOGY (2004)
An accelerated assay for the identification of lifespan-extending interventions in Drosophila melanogaster
JH Bauer et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Polyisoprenylated benzophenone, garcinol, a natural histone acetyltransferase inhibitor, represses chromatin transcription and alters global gene expression
K Balasubramanyam et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Sirtuin activators mimic caloric restriction and delay ageing in metazoans
JG Wood et al.
NATURE (2004)
Sir2 mediates longevity in the fly through a pathway related to calorie restriction
B Rogina et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
The arachidonic acid 5-lipoxygenase inhibitor nordihydroguaiaretic acid inhibits tumor necrosis factor α activation of microglia and extends survival of G93A-SOD1 transgenic mice
M West et al.
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Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
KT Howitz et al.
NATURE (2003)
Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans
CT Murphy et al.
NATURE (2003)
A dietary supplement abolishes age-related cognitive decline on transgenic mice expressing elevated free radical processes
JA Lemon et al.
EXPERIMENTAL BIOLOGY AND MEDICINE (2003)
Dose-dependent effect of melatonin on life span and spontaneous tumor incidence in female SHR mice
VN Anisimov et al.
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Association between telomere length in blood and mortality in people aged 60 years or older
RM Cawthon et al.
LANCET (2003)
Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence
E Langley et al.
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CD Rollo
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GP Lim et al.
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EM Williamson
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Melatonin increases both life span and tumor incidence in female CBA mice
VN Anisimov et al.
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