期刊
MEDICINA CLINICA
卷 152, 期 11, 页码 450-457出版社
ELSEVIER ESPANA SLU
DOI: 10.1016/j.medcli.2018.11.019
关键词
Ovulatory dysfunction; Hyperandrogenism; Obesity; Subfertility
Polycystic ovary syndrome is the most prevalent endocrine-metabolic pathology in pre-menopausal women. Its etiopathogenesis is complex, multifactorial and heterogeneous, including the interaction of genetic, epigenetic and environmental factors. Androgenic excess constitutes the disease's main physiopathological mechanism and results in reproductive, metabolic and cosmetic alterations which negatively impact these patients' quality of life. The criteria established in the Rotterdam consensus and their correct application form the necessary basis for this syndrome's proper diagnosis. In the absence of an aetiological treatment, the aim is to improve the clinical signs and symptoms derived from hyperandrogenism, ovarian dysfunction and existing metabolic complications, and, therefore, they must be chronic and individualised. (C) 2018 Elsevier Espana, S.L.U. All rights reserved.
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