期刊
MACROMOLECULAR BIOSCIENCE
卷 19, 期 4, 页码 -出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/mabi.201800458
关键词
biomaterials; controlled release; diabetes mellitus; insulin; non-invasive delivery; smart delivery systems
Diabetes mellitus (DM) is the most prevalent non-contagious disease, which has affected a large number of people all over the world. Among all treatments known to have a positive influence in the control of DM, insulin therapy is the most common and effective one. Nowadays, various methods of insulin delivery are under investigation, which are able to reach a plausible bioavailability with ignorable side effects instead of insulin injection. This article presents a comprehensive review of the insulin therapy approach with a focus on modified methods in insulin delivery strategies and current advances in engineered insulin delivery systems.
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