Design and investigation of ytterbium tungstate nanoparticles: An efficient catalyst for the sensitive and selective electrochemical detection of antipsychotic drug chlorpromazine

In this work, we have developed ytterbium tungstate (Yb2WO6) as an electrocatalyst through a simple co-precipitation method. The as-prepared catalyst was systematically investigated by various characterization techniques such as X-ray diffraction (XRD), Raman spectroscopy, field emission-scanning electron microscopy (FE-SEM) and energy-dispersive X-ray analysis (EDX). The as-developed Yb2WO6 was successfully applied to the electrochemical sensor (electrocatalyst) for sensitive and selective detection of antipsychotic drug chlorpromazine (CPZ). Interestingly, the Yb2WO6 modified screen printed carbon electrode (Yb2WO6/SPCE) shows an excellent electrocatalytic activity towards CPZ with extented wide linear response range and lower detection limit of 0.01-2520 mu M and 0.001 mu M, respectively. Moreover, the as-developed Yb2WO6/SPCE delivered an excellent selectivity even in the existence of cation, anion and some biologically co-interfering compounds. Furthermore, the Yb2WO6/SPCE displays an appreciable stability, and repeatability towards CPZ sensing. In addition, the Yb2WO6/SPCE was successfully applied to real sample analysis in CPZ tablet and urine samples with acceptable recoveries. (C) 2018 Taiwan Institute of Chemical Engineers. Published by Elsevier B.V. All rights reserved.