期刊
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
卷 140, 期 50, 页码 17333-17337出版社
AMER CHEMICAL SOC
DOI: 10.1021/jacs.8b08469
关键词
-
资金
- National Science Foundation [CHE-1566065]
Because of their inherent instability, hydro-persulfides (RSSH) must be generated in situ using precursors, but very few physiologically useful RSSH precursors have been developed to date. In this work, we report the design, synthesis, and evaluation of novel S-substituted thiosiothioureas as RSSH precursors. These water-soluble precursors show efficient and controllable release of RSSH under physiological conditions.
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