期刊
ACS APPLIED MATERIALS & INTERFACES
卷 8, 期 20, 页码 12638-12643出版社
AMER CHEMICAL SOC
DOI: 10.1021/acsami.6b02178
关键词
multiscale; TiO2 nanorod array; circulating tumor cells; high efficient capture
资金
- National Natural Science Foundation of China [21305154, 21275156]
- Natural Science of Foundation of Jiangsu Province [BK20130351]
- State Key Laboratory of Electroanalytical Chemistry [SKLEAC201410]
- CAS
- CAS/SAFEA International Innovation Teams program
In this work, a uniform multiscale TiO2 nanorod array is fabricated to provide a multi -scale interacting platform for cell capture, which exhibits excellent capture specificity and sensitivity of the target cells after modification with bovine serum albumin (BSA) and DNA aptamer. After studying the capture performance of the BSA-aptamer TiO2 nanorod substrates and other nanostructured substrates, we can conclude that the multisacle TiO2 nanorod substrates could indeed effectively enhance the capture yields of target cancer cells. The capture yield of artificial blood samples on
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