期刊
JOURNAL OF NUTRITION HEALTH & AGING
卷 23, 期 2, 页码 181-194出版社
SPRINGER FRANCE
DOI: 10.1007/s12603-018-1143-0
关键词
Dietary pattern; diet quality; mortality; cardiovascular disease; Chinese
资金
- Research Grants Council of Hong Kong [CUHK 4101/02M]
- Health and Medical Research Fund of the Food and Health Bureau of Hong Kong (HMRF) [12133811]
- Hong Kong Jockey Club Charities Trust
- Centre for Nutritional Studies, The Chinese University of Hong Kong
IntroductionStudies examining dietary patterns and inflammageing in relation to mortality are limited.ObjectiveWe examined the influence of various dietary patterns on all-cause and cardiovascular disease (CVD) mortality, taking into account demographics, lifestyle factors, and serum inflammatory markers.MethodsWe conducted multivariate Cox regression analyses using data from a cohort of communitydwelling older Chinese adults (1,406 men, 1,396 women) in Hong Kong. Baseline interviewer administered questionnaires covered dietary intake estimation and dietary pattern generation from the food frequency questionnaire, demographic and lifestyle factors, cognitive function and depressive symptoms. Serum high-sensitivity C-reactive protein (hsCRP) and 25-hydroxyvitamin D (25OHD) were measured. All-cause and CVD mortality data at 14-year follow up were retrieved from an official database.ResultsIn men, higher hsCRP level was associated with lower Diet Quality Index-International (DQI-I) score, Mediterranean-DASH Intervention for Neurodegenerative Delay Diet (MIND) score, Okinawan diet score, vegetables-fruits pattern score and snacks-drinks-milk pattern score. Higher serum 25OHD level was associated with higher Mediterranean Diet Score (MDS) but lower snacks-drinks-milk pattern score. None of the dietary pattern scores was associated with all-cause or CVD mortality after adjusting for all covariates. In women, hsCRP level and serum 25OHD level were not associated with any dietary patterns. Higher DQI-I score (HR=0.77 (95% CIs: 0.59, 0.99) highest vs. lowest tertile, p-trend=0.038) and Okinawan diet score (HR=0.78 (95% CIs: 0.61, 1.00) highest vs lowest tertile, p-trend=0.046) was associated with a lower risk of all-cause mortality, whereas higher MIND score (HR=0.63 (95% CI: 0.36, 1.09) highest vs. lowest tertile, p-trend=0.045) was associated with a reduced risk of CVD morality in the multivariate adjusted model.ConclusionHigher DQI-I score and Okinawan diet score were associated with a lower risk of all-cause mortality, and higher adherence to the MIND diet was related to a reduced risk of CVD mortality in community-dwelling Chinese older women.
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