期刊
JOURNAL OF MEDICAL PRIMATOLOGY
卷 48, 期 1, 页码 54-57出版社
WILEY
DOI: 10.1111/jmp.12381
关键词
16S rRNA; HIV; lavage; swab
资金
- National Institute of Diabetes and Digestive and Kidney Diseases [K01DK110264]
- National Institute of Allergy and Infectious Diseases [K01OD023034, R03 AI13879]
- California National Primate Research Center [P51 OD011107]
Cervicovaginal bacteria cause inflammation which in turn increases HIV risk. Profiling the cervicovaginal microbiome, therefore, is instrumental for vaccine development. We show that the microbiome profile captured by cervicovaginal lavage is comparable to samples obtained by vaginal swabs. Thus, lavage may serve as a sampling strategy in NHP vaccine studies.
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