Sensing and Manipulation of Bianisotropic Biomolecules Using a Surface Plasmon Resonance Based Optical Fiber Sensor

We report a mechanism to sense and manipulate bianisotropic chiral biomolecules by a surface plasmon resonance based side-polished optical fiber sensor. To simulate such planar layered structure containing anisotropic and magnetoelectric coupling biomolecules, the propagation matrix method is expanded. This method allows us to access the radiation pressure exerted on the bianisotropic molecular layer via the derivation of the Maxwell stress tensor. The complicated behavior of incident plane waves on the sensing and trapping of biomolecules with different medium parameters is clarified. We find that the optical fiber sensor is capable of simultaneous detection of chirality parameter, anisotropy, and refractive index of biomolecules. The structure can also be used to separate chiral molecules from achiral ones by using an emerging sharp surface plasmon resonance. The paper may provide new insights for SPR based sensors and imaging systems, optical tweezers, and nanomechnical devices.