期刊
JOURNAL OF INTERNATIONAL MEDICAL RESEARCH
卷 47, 期 1, 页码 281-292出版社
SAGE PUBLICATIONS LTD
DOI: 10.1177/0300060518800611
关键词
Multi-slice spiral computed tomography; metastatic lymph node; N-stage; gastric cancer; lesion infiltrates; diagnostic criteria
资金
- Natural Science Foundation of Jiangsu [BK20151334]
- Zhenjiang Innovation Capacity Project [SS2015023]
- Zhenjiang Municipal Commission of Health and Family Planning [SHW2015005]
Objective To establish new diagnostic criteria for improvement of the accuracy of multi-slice spiral computed tomography (MSCT) in diagnosing the N-stage and lymph node (LN) metastasis of gastric cancer (GC). Methods MSCT was performed with plain and triphasic dynamic contrast enhancement. Different regions of LN metastasis and N-staging were determined according to the herein-proposed combined diagnostic criteria and were then correlated with the pathological analysis. The Kappa consistency test was used to study the accuracy of MSCT. Results The accuracy of MSCT in diagnosing the N-stage as a whole was 86.3%, and that in diagnosing LN metastasis was 79.1% to 98.9%. The Kappa values for stages N0, N1, and N3 ranged from 0.449 to 0.662, indicating good consistency in diagnosing these three stages between MSCT and the postsurgical pathological results. The K-total value was 0.567 between MSCT and the postsurgical pathological results in diagnosing LN metastasis. The risk of LN metastasis increased with the progression of lesion infiltrates. Conclusions Application of the combined diagnostic criteria increased the diagnostic performance of MSCT in not only judging the N-stage but also diagnosing LN metastasis. This study will provide valuable reference data for surgical planning for patients with GC in the clinical setting.
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