期刊
JOURNAL OF INFECTIOUS DISEASES
卷 219, 期 7, 页码 1044-1048出版社
OXFORD UNIV PRESS INC
DOI: 10.1093/infdis/jiy620
关键词
Biocides; infectivity; inactivation; hepatitis B virus; HepG2-NTCP; virion stability
资金
- National Research Foundation of Korea [NRF-2017M3A9G6068246]
- German Society for hospital hygiene (DGKH)
Hepatitis B virus (HBV) infection is considered a major public health problem worldwide, and a significant number of reports on nosocomial and occupational outbreaks have been reported. This systematic investigation of HBV stability and susceptibility to different antiseptics revealed that HBV infectivity was very stable, with a half-life of >22 days at 37 degrees C. At 4 degrees C, infectivity was barely reduced for up to 9 months. Different alcohols and commercially available hand antiseptics had a virucidal effect against HBV. We propose that very strict compliance with established hygienic guidelines should be mandatory to avoid and prevent HBV infections.
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