期刊
JOURNAL OF INFECTIOUS DISEASES
卷 220, 期 6, 页码 951-955出版社
OXFORD UNIV PRESS INC
DOI: 10.1093/infdis/jiz025
关键词
hepatitis E virus; Hepeviridae; phylogenetic analysis; Western blot; immunocompetent
资金
- Public Health Agency of Canada
Hepatitis E virus (HEV) is a major public health concern in developing countries where the primary transmission is via contaminated water. Zoonotic HEV cases have been increasingly described in Europe, Japan, and the United States, with pigs representing the main animal reservoir of infection. We report an unusual acute hepatitis infection in a previously healthy man caused by a rat HEV with a considerably divergent genomic sequence compared with other rat HEV strains. It is possible that rat HEV is an underrecognized cause of hepatitis infection, and further studies are necessary to elucidate its potential risk and mode of transmission.
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