phytosynthesis of zinc oxide nanoparticles and its antibacterial, antiquorum sensing, antimotility, and antioxidant capacities against multidrug resistant bacteria

It was used green biosynthesized zinc oxide (ZnO) NPs (average diameter of 50-60 nm) with abilities of antibacterial against sensetive and MDR bacteria including Escherichia coli ATCC 25922, Serratia marcescens ATCC13880, Pseudomonas aeruginosa ATCC 27853 (gram negative), and Staphylococcus aureus ATCC 43300 and Staphylococcus epidermidis ATCC 12258 (gram positive). High reduction in biofilm formation was 63.43% (0.562 +/- 0.015) and 62.88% (0.582 +/- 0.025) at 100 mu g/mL concentration against control for S. epidermidis and P. aeruginosa respectively. In conclusion, this investigation illustrated simple green synthesis of ZnO NPs with suitable advantages of antioxidant, antibacterial, anti-biofilm, anti-QS activities, and also anti-swarming motility against MDR bacteria. (C) 2019 The Korean Society of Industrial and Engineering Chemistry. Published by Elsevier B.V. All rights reserved.