期刊
JOURNAL OF HETEROCYCLIC CHEMISTRY
卷 55, 期 12, 页码 2744-2759出版社
WILEY
DOI: 10.1002/jhet.3336
关键词
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Azole derivatives (10a-f) obtained starting from 1-(4-fluorohenyl)piperazine were converted to the corresponding Mannich bases (7a-d, 12a,b, and 16a,b) containing beta-lactame or flouroquinolone core via a one-pot three-component reaction. The synthesis of conazole analogues was carried out starting from triazole by three steps. Reactions were carried out under conventional-mediated and microwave-mediated conditions. All the newly synthesized compounds were screened for their antimicrobial, antioxidant activity, and most of them displayed good-moderate activity.
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